Literature DB >> 2801055

[Treatment of chronic osteomyelitis in Africa with plaster implants impregnated with antibiotics].

R Bouillet, B Bouillet, N Kadima, J Gillard.   

Abstract

Nineteen African patients with osteomyelitis were treated by curettage of the lesions and packing of the bone cavities with plaster of Paris pellets containing antibiotics (Fucidin and Amoxycillin). Of 18 patients followed, 16 showed wound healing in an average of 3 to 6 weeks. Eight patients had regular roentgenographic examinations during a minimum of two months. In six of these patients, healing of the lesions and a significant osteogenic reaction were observed. The plaster pellets were resorbed in 3 to 6 weeks in all patients, and no signs of rejection were noted. In spite of insufficient follow-up due to medical conditions in Africa (Zaire), the study confirms the advantages of this simple treatment of osteomyelitis in underdeveloped countries.

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Year:  1989        PMID: 2801055

Source DB:  PubMed          Journal:  Acta Orthop Belg        ISSN: 0001-6462            Impact factor:   0.500


  3 in total

1.  Biodegradable implants for potential use in bone infection. An in vitro study of antibiotic-loaded calcium sulphate.

Authors:  B Mousset; M A Benoit; C Delloye; R Bouillet; J Gillard
Journal:  Int Orthop       Date:  1995       Impact factor: 3.075

2.  PLGA and PHBV microsphere formulations and solid-state characterization: possible implications for local delivery of fusidic acid for the treatment and prevention of orthopaedic infections.

Authors:  Chiming Yang; David Plackett; David Needham; Helen M Burt
Journal:  Pharm Res       Date:  2009-04-21       Impact factor: 4.200

3.  Antimicrobial Formulations of Absorbable Bone Substitute Materials as Drug Carriers Based on Calcium Sulfate.

Authors:  D Pförringer; A Obermeier; M Kiokekli; H Büchner; S Vogt; A Stemberger; R Burgkart; M Lucke
Journal:  Antimicrob Agents Chemother       Date:  2016-06-20       Impact factor: 5.191

  3 in total

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