Literature DB >> 28009748

Mortality in Canadian Trauma Systems: A Multicenter Cohort Study.

Lynne Moore1, David Evans, Sayed M Hameed, Natalie L Yanchar, Henry T Stelfox, Richard Simons, John Kortbeek, Gilles Bourgeois, Julien Clément, François Lauzier, Avery Nathens, Alexis F Turgeon.   

Abstract

OBJECTIVE: To measure the variation in trauma center mortality across Canadian trauma systems, assess the contribution of traumatic brain injury and thoracoabdominal injury to observed variations, and evaluate whether the presence of recommended trauma system components is associated with mortality. SUMMARY BACKGROUND DATA: Injuries represent one of the leading causes of mortality, disability, and health care costs worldwide. Trauma systems have improved injury outcomes, but the impact of trauma system configuration on mortality is unknown.
METHODS: We conducted a retrospective cohort study of adults admitted for major injury to trauma centers across Canada (2006-2012). Multilevel logistic regression was used to estimate risk-adjusted hospital mortality and assess the impact of 13 recommended trauma system components.
RESULTS: Of 78,807 patients, 8382 (10.6%) died in hospital including 6516 (78%) after severe traumatic brain injury and 749 (9%) after severe thoracoabdominal injury. Risk-adjusted mortality varied from 7.0% to 14.2% across provinces (P < 0.0001); 11.1% to 26.0% for severe traumatic brain injury (P < 0.0001), and 4.7% to 5.9% for thoracoabdominal injury (P = 0.2). Mortality decreased with increasing number of recommended trauma system elements; adjusted odds ratio = 0.93 (0.87-0.99).
CONCLUSIONS: We observed significant variation in trauma center mortality across Canadian provinces, specifically for severe traumatic brain injury. Provinces with more recommended trauma system components had better patient survival. Results suggest that trauma system configuration may be an important determinant of injury mortality. A better understanding of which system processes drive optimal outcomes is required to reduce the burden of injury worldwide.

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Year:  2017        PMID: 28009748     DOI: 10.1097/SLA.0000000000001614

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  16 in total

1.  Trauma center need: the American College of Surgeons' definition in contrast to Swiss highly specialized medicine regulations-a Swiss trauma center perspective.

Authors:  Thomas Gross; Philipp Braken; Felix Amsler
Journal:  Eur J Trauma Emerg Surg       Date:  2018-10-13       Impact factor: 3.693

Review 2.  Impact of Trauma System Structure on Injury Outcomes: A Systematic Review and Meta-Analysis.

Authors:  Lynne Moore; Howard Champion; Pier-Alexandre Tardif; Brice-Lionel Kuimi; Gerard O'Reilly; Ari Leppaniemi; Peter Cameron; Cameron S Palmer; Fikri M Abu-Zidan; Belinda Gabbe; Christine Gaarder; Natalie Yanchar; Henry Thomas Stelfox; Raul Coimbra; John Kortbeek; Vanessa K Noonan; Amy Gunning; Malcolm Gordon; Monty Khajanchi; Teegwendé V Porgo; Alexis F Turgeon; Luke Leenen
Journal:  World J Surg       Date:  2018-05       Impact factor: 3.352

3.  Canadian benchmarks for acute injury care.

Authors:  Lynne Moore; David Evans; Natalie L Yanchar; Jaimini Thakore; Henry Thomas Stelfox; Morad Hameed; Richard Simons; John Kortbeek; Julien Clément; François Lauzier; Alexis F Turgeon
Journal:  Can J Surg       Date:  2017-12       Impact factor: 2.089

4.  Low-value clinical practices in injury care: a scoping review protocol.

Authors:  Lynne Moore; Khadidja Malloum Boukar; Pier-Alexandre Tardif; Henry T Stelfox; Howard Champion; Peter Cameron; Belinda Gabbe; Natalie Yanchar; John Kortbeek; François Lauzier; France Légaré; Patrick Archambault; Alexis F Turgeon
Journal:  BMJ Open       Date:  2017-07-12       Impact factor: 2.692

5.  Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study.

Authors:  Jilske A Huijben; Victor Volovici; Maryse C Cnossen; Iain K Haitsma; Nino Stocchetti; Andrew I R Maas; David K Menon; Ari Ercole; Giuseppe Citerio; David Nelson; Suzanne Polinder; Ewout W Steyerberg; Hester F Lingsma; Mathieu van der Jagt
Journal:  Crit Care       Date:  2018-04-13       Impact factor: 9.097

Review 6.  Neurotrauma: The Crosstalk between Neurotrophins and Inflammation in the Acutely Injured Brain.

Authors:  Lindolfo da Silva Meirelles; Daniel Simon; Andrea Regner
Journal:  Int J Mol Sci       Date:  2017-05-18       Impact factor: 5.923

7.  Development of the major trauma case review tool.

Authors:  Kate Curtis; Rebecca Mitchell; Amy McCarthy; Kellie Wilson; Connie Van; Belinda Kennedy; Gary Tall; Andrew Holland; Kim Foster; Stuart Dickinson; Henry T Stelfox
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2017-02-28       Impact factor: 2.953

8.  Ten-year inhospital mortality trends for patients with trauma in Japan: a multicentre observational study.

Authors:  Isao Nagata; Toshikazu Abe; Masatoshi Uchida; Daizoh Saitoh; Nanako Tamiya
Journal:  BMJ Open       Date:  2018-02-08       Impact factor: 2.692

9.  Economic evaluation of intrahospital clinical practices in injury care: protocol for a 10-year systematic review.

Authors:  Blanchard Conombo; Jason Robert Guertin; Pier-Alexandre Tardif; Imen Farhat; Thomas Moore; Samy Bouderba; Kahina Soltana; Patrick Archambault; Simon Berthelot; François Lauzier; Alexis F Turgeon; Henry Thomas Stelfox; Michaël Chasse; Jeffrey Hoch; Lynne Moore
Journal:  BMJ Open       Date:  2020-07-14       Impact factor: 2.692

10.  Developing Emergency and Trauma Systems Internationally: What is Really Needed for Better Outcomes?

Authors:  Mazen J El Sayed
Journal:  J Emerg Trauma Shock       Date:  2017 Jul-Sep
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