Literature DB >> 28009351

S-2HG is an immunometabolite that shapes the T-cell response.

Rob A Cairns1, Tak W Mak1.   

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Year:  2016        PMID： 28009351      PMCID： PMC5299719          DOI： 10.1038/cdd.2016.149

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


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  6 in total

Review 1.  A guide to immunometabolism for immunologists.

Authors:  Luke A J O'Neill; Rigel J Kishton; Jeff Rathmell
Journal:  Nat Rev Immunol       Date:  2016-07-11       Impact factor: 53.106

2.  Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress.

Authors:  William M Oldham; Clary B Clish; Yi Yang; Joseph Loscalzo
Journal:  Cell Metab       Date:  2015-07-23       Impact factor: 27.287

3.  Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.

Authors:  David R Wise; Patrick S Ward; Jessica E S Shay; Justin R Cross; Joshua J Gruber; Uma M Sachdeva; Jesse M Platt; Raymond G DeMatteo; M Celeste Simon; Craig B Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-21       Impact factor: 12.779

Review 4.  Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities.

Authors:  Rob A Cairns; Tak W Mak
Journal:  Cancer Discov       Date:  2013-06-24       Impact factor: 38.272

5.  S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate.

Authors:  Petros A Tyrakis; Asis Palazon; David Macias; Kian L Lee; Anthony T Phan; Pedro Veliça; Jia You; Grace S Chia; Jingwei Sim; Andrew Doedens; Alice Abelanet; Colin E Evans; John R Griffiths; Lorenz Poellinger; Ananda W Goldrath; Randall S Johnson
Journal:  Nature       Date:  2016-10-26       Impact factor: 49.962

6.  Hypoxia Induces Production of L-2-Hydroxyglutarate.

Authors:  Andrew M Intlekofer; Raymond G Dematteo; Sriram Venneti; Lydia W S Finley; Chao Lu; Alexander R Judkins; Ariën S Rustenburg; Patrick B Grinaway; John D Chodera; Justin R Cross; Craig B Thompson
Journal:  Cell Metab       Date:  2015-07-23       Impact factor: 31.373
  6 in total
  2 in total

1.  The immunometabolite S-2-hydroxyglutarate exacerbates perioperative ischemic brain injury and cognitive dysfunction by enhancing CD8+ T lymphocyte-mediated neurotoxicity.

Authors:  Faqiang Zhang; Mu Niu; Kaikai Guo; Zeguo Feng; Weidong Mi; Long Wang; Yulong Ma; Qiang Fu; Yanhong Liu
Journal:  J Neuroinflammation       Date:  2022-07-07       Impact factor: 9.587

Review 2.  Metabolic reprogramming and epigenetic modifications on the path to cancer.

Authors:  Linchong Sun; Huafeng Zhang; Ping Gao
Journal:  Protein Cell       Date:  2021-05-29       Impact factor: 15.328
  2 in total

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