| Literature DB >> 28009021 |
Ramon Subiros-Funosas1, Lorena Mendive-Tapia2, Jesus Sot3, John D Pound1, Nicole Barth1, Yaiza Varela3, Felix M Goñi3, Margaret Paterson1, Christopher D Gregory1, Fernando Albericio4, Ian Dransfield1, Rodolfo Lavilla5, Marc Vendrell1.
Abstract
The rational design and synthesis of a Trp-BODIPY cyclic peptide for the fluorescent labelling of apoptotic bodies is described. Affinity assays, confocal microscopy and flow cytometry analysis confirmed the binding of the peptide to negatively-charged phospholipids associated with apoptosis, and its applicability for the detection and characterisation of subcellular structures released by apoptotic cells.Entities:
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Year: 2017 PMID： 28009021 DOI： 10.1039/c6cc07879f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222