Literature DB >> 28008602

MicroRNA-335-5p and -3p synergize to inhibit estrogen receptor alpha expression and promote tamoxifen resistance.

Elizabeth C Martin1, Adrienne K Conger2, Thomas J Yan3, Van T Hoang3, David F B Miller4, Aaron Buechlein5, Douglas B Rusch5, Kenneth P Nephew4, Bridgette M Collins-Burow3, Matthew E Burow3,6,7.   

Abstract

microRNAs (miRNAs) are small noncoding RNA molecules involved in the regulation of gene expression and play critical roles in human malignancies. Next-generation sequencing analysis of the MCF-7 breast cancer cell line overexpressing miR-335-5p and miR-335-3p demonstrated that the miRNA duplex repressed genes involved in the ERα signaling pathway, and enhanced resistance of MCF-7 cells to the growth inhibitory effects of tamoxifen. These data suggest that despite its conventional role in tumor suppression, the miR-335 transcript can also play an oncogenic role in promoting agonistic estrogen signaling in a cancerous setting.
© 2016 Federation of European Biochemical Societies.

Entities:  

Keywords:  breast cancer; endocrine resistance; estrogen receptor; isoform; miRNA-335; microRNA

Mesh：

Substances：

Year:  2017        PMID： 28008602      PMCID： PMC5853108          DOI： 10.1002/1873-3468.12538

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  40 in total

1.  MicroRNA-27a Indirectly Regulates Estrogen Receptor {alpha} Expression and Hormone Responsiveness in MCF-7 Breast Cancer Cells.

Authors:  Xiangrong Li; Susanne U Mertens-Talcott; Shu Zhang; Kyounghyun Kim; Judith Ball; Stephen Safe
Journal:  Endocrinology       Date:  2010-04-09       Impact factor: 4.736

2.  ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis.

Authors:  Sofie Svensson; Karin Jirström; Lisa Rydén; Göran Roos; Stefan Emdin; Michael C Ostrowski; Göran Landberg
Journal:  Oncogene       Date:  2005-06-23       Impact factor: 9.867

Review 3.  Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy.

Authors:  Xiaojiang Cui; Rachel Schiff; Grazia Arpino; C Kent Osborne; Adrian V Lee
Journal:  J Clin Oncol       Date:  2005-10-20       Impact factor: 44.544

4.  Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase.

Authors:  C M Pombo; J H Kehrl; I Sánchez; P Katz; J Avruch; L I Zon; J R Woodgett; T Force; J M Kyriakis
Journal:  Nature       Date:  1995-10-26       Impact factor: 49.962

5.  MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1.

Authors:  Tyler E Miller; Kalpana Ghoshal; Bhuvaneswari Ramaswamy; Satavisha Roy; Jharna Datta; Charles L Shapiro; Samson Jacob; Sarmila Majumder
Journal:  J Biol Chem       Date:  2008-08-15       Impact factor: 5.157

6.  Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells.

Authors:  Elizabeth C Martin; Steven Elliott; Lyndsay V Rhodes; James W Antoon; Claire Fewell; Yun Zhu; Jennifer L Driver; Mona Jodari-Karimi; Christopher W Taylor; Erik K Flemington; Barbara S Beckman; Bridgette M Collins-Burow; Matthew E Burow
Journal:  Mol Carcinog       Date:  2012-08-21       Impact factor: 4.784

7.  The UCSC Cancer Genomics Browser: update 2011.

Authors:  J Zachary Sanborn; Stephen C Benz; Brian Craft; Christopher Szeto; Kord M Kober; Laurence Meyer; Charles J Vaske; Mary Goldman; Kayla E Smith; Robert M Kuhn; Donna Karolchik; W James Kent; Joshua M Stuart; David Haussler; Jingchun Zhu
Journal:  Nucleic Acids Res       Date:  2010-11-08       Impact factor: 16.971

8.  Dual regulation by microRNA-200b-3p and microRNA-200b-5p in the inhibition of epithelial-to-mesenchymal transition in triple-negative breast cancer.

Authors:  Lyndsay V Rhodes; Elizabeth C Martin; H Chris Segar; David F B Miller; Aaron Buechlein; Douglas B Rusch; Kenneth P Nephew; Matthew E Burow; Bridgette M Collins-Burow
Journal:  Oncotarget       Date:  2015-06-30

9.  The UCSC Cancer Genomics Browser: update 2013.

Authors:  Mary Goldman; Brian Craft; Teresa Swatloski; Kyle Ellrott; Melissa Cline; Mark Diekhans; Singer Ma; Chris Wilks; Josh Stuart; David Haussler; Jingchun Zhu
Journal:  Nucleic Acids Res       Date:  2012-10-29       Impact factor: 16.971

10.  Endocrine resistance in breast cancer: Current status and a perspective on the roles of miRNAs (Review).

Authors:  Jichun Zhou; Rongyue Teng; Qinchuan Wang; Chenpu Xu; Jufeng Guo; Chao Yuan; Jianguo Shen; Wenxian Hu; Linbo Wang; Shuduo Xie
Journal:  Oncol Lett       Date:  2013-06-17       Impact factor: 2.967
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  17 in total

Review 1.  Regulation of breast cancer metastasis signaling by miRNAs.

Authors:  Belinda J Petri; Carolyn M Klinge
Journal:  Cancer Metastasis Rev       Date:  2020-09       Impact factor: 9.264

2.  Mirna biogenesis pathway is differentially regulated during adipose derived stromal/stem cell differentiation.

Authors:  E C Martin; A T Qureshi; C B Llamas; M E Burow; A G King; O C Lee; V Dasa; M A Freitas; J A Forsberg; E A Elster; T A Davis; J M Gimble
Journal:  Adipocyte       Date:  2018-02-07       Impact factor: 4.534

3.  miR-1268a regulates ABCC1 expression to mediate temozolomide resistance in glioblastoma.

Authors:  Yaomin Li; Yawei Liu; Jing Ren; Shengze Deng; Guozhong Yi; Manlan Guo; Songren Shu; Liang Zhao; Yuping Peng; Songtao Qi
Journal:  J Neurooncol       Date:  2018-06-06       Impact factor: 4.130

4.  Circular RNA TLK1 Aggravates Neuronal Injury and Neurological Deficits after Ischemic Stroke via miR-335-3p/TIPARP.

Authors:  Fangfang Wu; Bing Han; Shusheng Wu; Li Yang; Shuo Leng; Mingyue Li; Jiefeng Liao; Guangtian Wang; Qingqing Ye; Yuan Zhang; Haifeng Chen; Xufeng Chen; Ming Zhong; Yun Xu; Qiang Liu; John H Zhang; Honghong Yao
Journal:  J Neurosci       Date:  2019-07-16       Impact factor: 6.167

Review 5.  microRNA Regulation in Estrogen Receptor-Positive Breast Cancer and Endocrine Therapy.

Authors:  Erin W Howard; Xiaohe Yang
Journal:  Biol Proced Online       Date:  2018-09-11       Impact factor: 3.244

Review 6.  The Network of Non-coding RNAs in Cancer Drug Resistance.

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Journal:  Front Oncol       Date:  2018-08-29       Impact factor: 6.244

7.  MicroRNA-335/ID4 dysregulation predicts clinical outcome and facilitates leukemogenesis by activating PI3K/Akt signaling pathway in acute myeloid leukemia.

Authors:  Jing-Dong Zhou; Xi-Xi Li; Ting-Juan Zhang; Zi-Jun Xu; Zhi-Hui Zhang; Yu Gu; Xiang-Mei Wen; Wei Zhang; Run-Bi Ji; Zhao-Qun Deng; Jiang Lin; Jun Qian
Journal:  Aging (Albany NY)       Date:  2019-05-30       Impact factor: 5.682

Review 8.  MicroRNAs and Epigenetics Strategies to Reverse Breast Cancer.

Authors:  Mohammad Mijanur Rahman; Andrew C Brane; Trygve O Tollefsbol
Journal:  Cells       Date:  2019-10-08       Impact factor: 6.600

9.  Bioinformatics-based identification of miR-542-5p as a predictive biomarker in breast cancer therapy.

Authors:  Qiong-Ni Zhu; Helen Renaud; Ying Guo
Journal:  Hereditas       Date:  2018-01-15       Impact factor: 3.271

10.  Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial.

Authors:  Ines Stevic; Volkmar Müller; Karsten Weber; Peter A Fasching; Thomas Karn; Frederic Marmé; Christian Schem; Elmar Stickeler; Carsten Denkert; Marion van Mackelenbergh; Christoph Salat; Andreas Schneeweiss; Klaus Pantel; Sibylle Loibl; Michael Untch; Heidi Schwarzenbach
Journal:  BMC Med       Date:  2018-10-10       Impact factor: 8.775
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