Literature DB >> 28005110

Biomechanics of Polyhydroxyalkanoate Mesh-Augmented Single-Row Rotator Cuff Repairs.

Robert Z Tashjian, Christopher W Kolz, Thomas Suter, Heath B Henninger1.   

Abstract

Polyhydroxyalkanoate (PHA) mesh is a bioresorbable scaffold used to reinforce the suture-tendon interface in rotator cuff repairs (RCRs). We conducted a study of cyclic and ultimate failure properties of PHA mesh-augmented single-row RCRs and nonaugmented RCRs. Eight pairs of fresh-frozen cadaver humeri (6 male, 2 female) were tested. Mean (SD) age was 61 (9) years. The supraspinatus tendon was resected and reattached in a single-row configuration using 2 triple-loaded suture anchors and 6 simple stitches. The opposite humerus underwent RCR augmented with 2 strips of 13-mm × 23-mm PHA mesh. Humeri were mounted in an Instron load frame, cycled 1000 times to 1.0 MPa of effective stress, and loaded to failure. Construct gapping and ultimate failure loads/displacements were recorded. Paired t tests compared augmented and nonaugmented RCRs (P ≤ .05 was significant). There was no difference in gapping over 1000 cycles (P = .879). Mean (SD) failure load was higher for PHA mesh-augmented RCRs, 571 (173) N, than for nonaugmented (control) RCRs, 472 (120) N (P = .042), and failures were consistent within pairs because of tissue failure at the knots or anchor pullout. This technique for arthroscopic augmentation can be used to improve initial biomechanical repair strength in tears at risk for failure.

Entities:  

Mesh:

Substances:

Year:  2016        PMID: 28005110

Source DB:  PubMed          Journal:  Am J Orthop (Belle Mead NJ)        ISSN: 1078-4519


  2 in total

Review 1.  Nonreconstruction Options for Treating Medial Ulnar Collateral Ligament Injuries of the Elbow in Overhead Athletes.

Authors:  Nicholas J Clark; Vishal S Desai; Joshua D Dines; Mark E Morrey; Christopher L Camp
Journal:  Curr Rev Musculoskelet Med       Date:  2018-03

Review 2.  Recent Advances in the Use of Polyhydroyalkanoates in Biomedicine.

Authors:  Alejandra Rodriguez-Contreras
Journal:  Bioengineering (Basel)       Date:  2019-09-12
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.