Literature DB >> 28004156

[Intramuscular depot steroids : Possible treatment of postsurgical cystoid macula edema with steroid response?]

A-M Seuthe1, P Szurman2,3, K T Boden2.   

Abstract

We report on a patient with postsurgical cystoid macular edema (CME) after phacoemulsification and multifocal intraocular lens (MIOL) implantation. At first, there was a very good reaction to intravitreal triamcinolone, inducing complete regression of the edema without increasing intraocular pressure (IOP). One year later the patient suffered from retinal detachment and was treated with vitrectomy, laser, and gas tamponade. Afterward, he developed macular pucker with edema. After surgical treatment with pucker peeling and intravitreal triamcinolone, the patient showed a steroid response and an increase IOP. Postoperatively, there was a recurrence of CME. A coincidental administration of a steroid injection intramuscularly by the general practitioner achieved a prompt reduction of the CME without increasing IOP. This case shows that an initially good reaction to triamcinolone without increasing IOP does not rule out a future steroid response, and that a potential treatment option for CME in patients with a known steroid response could consist of intramuscularly injected steroids.

Entities:  

Keywords:  Intramuscular steroid application; Intraocular pressure increase; Postoperative cystoid macular edema; Steroid response; Triamcinolone

Mesh:

Substances:

Year:  2017        PMID: 28004156     DOI: 10.1007/s00347-016-0425-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  10 in total

Review 1.  Pharmacologic therapy of pseudophakic cystoid macular edema: 2010 update.

Authors:  Heather N Shelsta; Lee M Jampol
Journal:  Retina       Date:  2011-01       Impact factor: 4.256

2.  [Advantages of acetazolamide associated with anti-inflammatory medications in postoperative treatment of macular edema].

Authors:  A Catier; R Tadayoni; P Massin; A Gaudric
Journal:  J Fr Ophtalmol       Date:  2005-12       Impact factor: 0.818

3.  Intraocular pressure elevation after intravitreal or posterior sub-Tenon triamcinolone acetonide injection.

Authors:  Yumiko Yamamoto; Tsutomu Komatsu; Yuji Koura; Koji Nishino; Atsuki Fukushima; Hisayuki Ueno
Journal:  Can J Ophthalmol       Date:  2008-02       Impact factor: 1.882

4.  Steroid differentiation: the safety profile of various steroids on retinal cells in vitro and their implications for clinical use (an American Ophthalmological Society thesis).

Authors:  Baruch D Kuppermann; Leandro Cabral Zacharias; M Cristina Kenney
Journal:  Trans Am Ophthalmol Soc       Date:  2014-07

Review 5.  Pseudophakic cystoid macular edema.

Authors:  Conceição Lobo
Journal:  Ophthalmologica       Date:  2011-09-15       Impact factor: 3.250

6.  [Intravitreal dexamethasone implant for treatment of persistent postoperative macular edema after vitrectomy].

Authors:  L-O Hattenbach; C Kuhli-Hattenbach; C Springer; J Callizo; H Hoerauf
Journal:  Ophthalmologe       Date:  2016-07       Impact factor: 1.059

7.  Dexamethasone posterior-segment drug delivery system in the treatment of macular edema resulting from uveitis or Irvine-Gass syndrome.

Authors:  George A Williams; Julia A Haller; Baruch D Kuppermann; Mark S Blumenkranz; David V Weinberg; Connie Chou; Scott M Whitcup
Journal:  Am J Ophthalmol       Date:  2009-03-09       Impact factor: 5.258

8.  Postsurgical cystoid macular edema.

Authors:  Dina Zur; Naomi Fischer; Adnan Tufail; Jordi Monés; Anat Loewenstein
Journal:  Eur J Ophthalmol       Date:  2011       Impact factor: 2.597

9.  Intravitreal bevacizumab for pseudophakic cystoid macular edema; a systematic review.

Authors:  Khalil Ghasemi Falavarjani; Mohammad-Mehdi Parvaresh; Mehdi Modarres; Masih Hashemi; Nasrollah Samiy
Journal:  J Ophthalmic Vis Res       Date:  2012-07

10.  Strong topical steroid, NSAID, and carbonic anhydrase inhibitor cocktail for treatment of cystoid macular edema.

Authors:  Masumi G Asahi; Gabriela L Bobarnac Dogaru; Spencer M Onishi; Ron P Gallemore
Journal:  Int Med Case Rep J       Date:  2015-12-01
  10 in total

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