Literature DB >> 28003373

Chronic Inflammation: Accelerator of Biological Aging.

Bertrand Fougère1,2, Eric Boulanger3, Fati Nourhashémi1,2, Sophie Guyonnet1,2, Matteo Cesari1,2.   

Abstract

Biological aging is characterized by a chronic low-grade inflammation level. This chronic phenomenon has been named "inflamm-aging" and is a highly significant risk factor for morbidity and mortality in the older persons. The most common theories of inflamm-aging include redox stress, mitochondrial dysfunction, glycation, deregulation of the immune system, hormonal changes, epigenetic modifications, and dysfunction telomere attrition. Inflamm-aging plays a role in the initiation and progression of age-related diseases such as type II diabetes, Alzheimer's disease, cardiovascular disease, frailty, sarcopenia, osteoporosis, and cancer. This review will cover the identification of pathways that control age-related inflammation across multiple systems and its potential causal role in contributing to adverse health outcomes.
© The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  aging; biology; chronic diseases; inflammation

Mesh：

Substances：

Year:  2017        PMID： 28003373     DOI： 10.1093/gerona/glw240

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN： 1079-5006            Impact factor:   6.053


  86 in total

1.  The relationship between interleukin-6 levels and physical performance in mobility-limited older adults with chronic low-grade inflammation: The ENRGISE Pilot study.

Authors:  Carlo Custodero; Stephen D Anton; Daniel P Beavers; Robert T Mankowski; Stephanie A Lee; Mary M McDermott; Roger A Fielding; Anne B Newman; Russel P Tracy; Stephen B Kritchevsky; Walter T Ambrosius; Marco Pahor; Todd M Manini
Journal:  Arch Gerontol Geriatr       Date:  2020-05-30       Impact factor: 3.250

2.  Soluble Tumor Necrosis Factor Alpha Receptor 1, Bone Resorption, and Bone Mineral Density in the Year Following Hip Fractures: The Baltimore Hip Studies.

Authors:  Shabnam Salimi; Michelle Shardell; Ram Miller; Ann L Gruber-Baldini; Denise Orwig; Neal Fedarko; Marc C Hochberg; Jack M Guralnik; Jay Magaziner
Journal:  J Bone Miner Res       Date:  2018-06-15       Impact factor: 6.741

3.  Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population.

Authors:  M Serra-Prat; I Lorenzo; E Palomera; S Ramírez; J C Yébenes
Journal:  J Nutr Health Aging       Date:  2019       Impact factor: 4.075

4.  Changes Due to Ageing in the Glycan Structure of Alpha-2-Macroglobulin and Its Reactivity with Ligands.

Authors:  Miloš Šunderić; Martina Križáková; Vesna Malenković; Danica Ćujić; Jaroslav Katrlík; Olgica Nedić
Journal:  Protein J       Date:  2019-02       Impact factor: 2.371

5.  Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis.

Authors:  C Custodero; R T Mankowski; S A Lee; Z Chen; S Wu; T M Manini; J Hincapie Echeverri; C Sabbà; D P Beavers; J A Cauley; M A Espeland; R A Fielding; S B Kritchevsky; C K Liu; M M McDermott; M E Miller; R P Tracy; A B Newman; W T Ambrosius; M Pahor; S D Anton
Journal:  Ageing Res Rev       Date:  2018-05-25       Impact factor: 10.895

6.  IL-1Rahigh-IL-4low-IL-13low: A Novel Plasma Cytokine Signature Associated with Olfactory Dysfunction in Older US Adults.

Authors:  Eli P Darnell; Kristen E Wroblewski; Kristina L Pagel; David W Kern; Martha K McClintock; Jayant M Pinto
Journal:  Chem Senses       Date:  2020-05-29       Impact factor: 3.160

7.  Topical applications of an emollient reduce circulating pro-inflammatory cytokine levels in chronically aged humans: a pilot clinical study.

Authors:  L Ye; T M Mauro; E Dang; G Wang; L Z Hu; C Yu; S Jeong; K Feingold; P M Elias; C Z Lv; M Q Man
Journal:  J Eur Acad Dermatol Venereol       Date:  2019-03-27       Impact factor: 6.166

8.  Short-term pharmacologic RAGE inhibition differentially affects bone and skeletal muscle in middle-aged mice.

Authors:  Hannah M Davis; Alyson L Essex; Sinai Valdez; Padmini J Deosthale; Mohammad W Aref; Matthew R Allen; Andrea Bonetto; Lilian I Plotkin
Journal:  Bone       Date:  2019-04-24       Impact factor: 4.398

9.  Systemic Tumor Necrosis Factor-Alpha Trajectories Relate to Brain Health in Typically Aging Older Adults.

Authors:  Cutter A Lindbergh; Kaitlin B Casaletto; Adam M Staffaroni; Fanny Elahi; Samantha M Walters; Michelle You; John Neuhaus; Will Rivera Contreras; Paul Wang; Anna Karydas; Jesse Brown; Amy Wolf; Howie Rosen; Yann Cobigo; Joel H Kramer
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2020-07-13       Impact factor: 6.053

Review 10.  Traumatic Stress and Accelerated Cellular Aging: From Epigenetics to Cardiometabolic Disease.

Authors:  Erika J Wolf; Filomene G Morrison
Journal:  Curr Psychiatry Rep       Date:  2017-08-29       Impact factor: 5.285
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