Literature DB >> 27997927

Correction: A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles.

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Abstract

[This corrects the article DOI: 10.1371/journal.pone.0157435.].

Entities:  

Year:  2016        PMID: 27997927      PMCID: PMC5173380          DOI: 10.1371/journal.pone.0169025

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


There is an error in Table 3. The values in columns Post-prime, Post-boost and Post-challenge were incorrectly omitted. The authors have provided a corrected version here. The publisher apologizes for the error.
Table 3

Reciprocal titres of anti-FMDV antibodies (serotype O) in sera from calves in experiment 3.

Post-primePost-boostPost-challenge
GroupVaccinationAnimalPVD 14PVD 28PVD 36
1No vaccination (control)C1--40
C2--40
C3--160
2rSFV-FMDV-P1-2A-mIRES-3C (PVD 0) + empty capsid particles (PVD 14)C4-3201280
C5-40320
C6203201280
3empty capsid particles (PVD 0) + rSFV-FMDV-P1-2A-mIRES-3C (PVD 14)C720205120
C8-805120
C9-105120

Calves were either unvaccinated (group 1) or vaccinated with rSFV-FMDV-P1-2A-mIRES-3C (on PVD 0) followed by empty capsid particles (on PVD 14) (group 2) or vaccinated with empty capsids on PVD 0 and then with rSFV-FMDV-P1-2A-mIRES-3C on PVD 14 (group 3). All cattle were challenged with FMDV by needle inoculation on PVD 28. Sera collected on PVD 14, 28 (pre-challenge) and 36 were titred in the blocking ELISA using 2-fold dilutions starting at 1:5.—indicates negative.

Calves were either unvaccinated (group 1) or vaccinated with rSFV-FMDV-P1-2A-mIRES-3C (on PVD 0) followed by empty capsid particles (on PVD 14) (group 2) or vaccinated with empty capsids on PVD 0 and then with rSFV-FMDV-P1-2A-mIRES-3C on PVD 14 (group 3). All cattle were challenged with FMDV by needle inoculation on PVD 28. Sera collected on PVD 14, 28 (pre-challenge) and 36 were titred in the blocking ELISA using 2-fold dilutions starting at 1:5.—indicates negative.
  1 in total

1.  A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles.

Authors:  Maria Gullberg; Louise Lohse; Anette Bøtner; Gerald M McInerney; Alison Burman; Terry Jackson; Charlotta Polacek; Graham J Belsham
Journal:  PLoS One       Date:  2016-06-13       Impact factor: 3.240

  1 in total
  1 in total

1.  Will a Single-Cycle Adenovirus Vaccine Be Effective Against Ebola Virus?

Authors:  Michael R Holbrook
Journal:  J Infect Dis       Date:  2018-11-05       Impact factor: 5.226

  1 in total

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