BACKGROUND: Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents. METHODS: The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files. RESULTS: Dyslipidemia prevalence was found to be 26.2%. Hypercholesterolemia (15.8%) and hyperglyceridemia (12.9%) were most common findings. Age, body mass index (BMI), hemoglobin A1c (A1C) and poor metabolic control were significantly higher in cases with dyslipidemia. Smoking rate was 14.1% in the pubertal group. Poor metabolic control and dyslipidemia was found higher among smokers (p<0.05). CONCLUSIONS: Blood lipid levels should be monitored regularly and nutrition education should be repeated periodically to prevent and control dyslipidemia in patients with T1D. Smoking-related risks should be a part of patient education in the pubertal period.
BACKGROUND:Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabeticchildren and adolescents. METHODS: The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files. RESULTS:Dyslipidemia prevalence was found to be 26.2%. Hypercholesterolemia (15.8%) and hyperglyceridemia (12.9%) were most common findings. Age, body mass index (BMI), hemoglobin A1c (A1C) and poor metabolic control were significantly higher in cases with dyslipidemia. Smoking rate was 14.1% in the pubertal group. Poor metabolic control and dyslipidemia was found higher among smokers (p<0.05). CONCLUSIONS: Blood lipid levels should be monitored regularly and nutrition education should be repeated periodically to prevent and control dyslipidemia in patients with T1D. Smoking-related risks should be a part of patient education in the pubertal period.
Authors: Benjamin Udoka Nwosu; Tony R Villalobos-Ortiz; Gabrielle A Jasmin; Sadichchha Parajuli; Emily Zitek-Morrison; Bruce A Barton Journal: J Pediatr Endocrinol Metab Date: 2020-11-26 Impact factor: 1.520
Authors: Benjamin Udoka Nwosu; Shwetha Rupendu; Emily Zitek-Morrison; Deepa Patel; Tony R Villalobos-Ortiz; Gabrielle Jasmin; Bruce A Barton Journal: J Endocr Soc Date: 2019-02-27
Authors: Benjamin Udoka Nwosu; Bo Zhang; Sanaa S Ayyoub; Stephanie Choi; Tony R Villalobos-Ortiz; Laura C Alonso; Bruce A Barton Journal: PLoS One Date: 2018-05-16 Impact factor: 3.240
Authors: Grace Kim; Daniel DeSalvo; Danielle Guffey; Charles G Minard; Constance Cephus; Douglas Moodie; Sarah Lyons Journal: Int J Pediatr Endocrinol Date: 2020-06-11
Authors: Lílian Caroline de Souza E Silva; Skalyt Lee Barbosa E Silva; Ávilla Monalisa Silva de Oliveira; Jacqueline Rosangela de Araujo; Ilma Kruze Grande de Arruda; Regiane Maio; Maria da Conceição Chaves de Lemos Journal: Rev Paul Pediatr Date: 2020-03-16