Matteo Donadon1, Luigi Solbiati2, Laura Dawson3, Aisling Barry3, Gonzalo Sapisochin4, Paul D Greig4, Shuichiro Shiina5, Andrea Fontana1, Guido Torzilli1. 1. Department of Hepatobiliary and General Surgery, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy. 2. Department of Interventional Radiology, Humanitas University, Humanitas Research Hospital IRCCS, Milan, Italy. 3. Department of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, Canada. 4. Deparments of General Surgery and Multi Organ Transplantation, Toronto General Hospital, University of Toronto, Toronto, Canada. 5. Department of Gastroenterology, Junten-do University Graduate School of Medicine, Tokyo, Japan.
Abstract
BACKGROUND: Hepatocellular carcinoma (HCC) remains a major health issue because of its increasing incidence and because of the complexity of its management. In addition to the traditional potentially curative treatments, i.e., liver transplantation and surgical resection, other new and emerging local therapies have been applied with promising results. SUMMARY: Radiotherapy (RT) and interstitial treatments, such as radiofrequency ablation (RFA), microwave ablation (MWA), and irreversible electroporation (IRE), have recently opened new and interesting treatment scenarios for HCC and are associated with promising results in selected patients. Herein, we describe the emerging role of interventional oncology for the treatment of HCC and focus on the different Western and Eastern approaches. KEY MESSAGES: Modern RT and modern interstitial therapies, such as RFA, MWA, and IRE, should be considered for inclusion in HCC therapy guidelines.
BACKGROUND: Hepatocellular carcinoma (HCC) remains a major health issue because of its increasing incidence and because of the complexity of its management. In addition to the traditional potentially curative treatments, i.e., liver transplantation and surgical resection, other new and emerging local therapies have been applied with promising results. SUMMARY: Radiotherapy (RT) and interstitial treatments, such as radiofrequency ablation (RFA), microwave ablation (MWA), and irreversible electroporation (IRE), have recently opened new and interesting treatment scenarios for HCC and are associated with promising results in selected patients. Herein, we describe the emerging role of interventional oncology for the treatment of HCC and focus on the different Western and Eastern approaches. KEY MESSAGES: Modern RT and modern interstitial therapies, such as RFA, MWA, and IRE, should be considered for inclusion in HCC therapy guidelines.
Entities:
Keywords:
IRE for HCC; MWA for HCC; RFA for HCC; Radiotherapy for HCC
Authors: J Scott Goodwin; Leo L Tsai; David Mwin; Patricia Coutinho de Souza; Svayam Dialani; John T Moon; Zheng Zhang; Aaron K Grant; Muneeb Ahmed Journal: Magn Reson Imaging Date: 2021-04-24 Impact factor: 3.130
Authors: Marie Beermann; Johan Lindeberg; Jennie Engstrand; Karolina Galmén; Silja Karlgren; David Stillström; Henrik Nilsson; Piotr Harbut; Jacob Freedman Journal: Eur J Radiol Open Date: 2018-12-05