Olufunke O Adeyeye1, Tomilola A Adewumi2, Abiodun O Adewuya3. 1. Lagos State University College of Medicine (LASUCOM), 1-5, Oba Akinjobi Way, Ikeja, Lagos, Nigeria. 2. Centre for Mental Health Research and Initiative (CEMHRI), Ikeja, Lagos, Nigeria. 3. Lagos State University College of Medicine (LASUCOM), 1-5, Oba Akinjobi Way, Ikeja, Lagos, Nigeria; Centre for Mental Health Research and Initiative (CEMHRI), Ikeja, Lagos, Nigeria. Electronic address: biodunwuya@yahoo.com.
Abstract
BACKGROUND: This study aimed to assess the effect of psychological and other possible factors associated with poor health related quality of life (HRQOL) in outpatient with asthma in Lagos, Nigeria. METHODS: Patients (n = 201) recruited from the adult asthma outpatient clinic were assessed for sociodemographic and asthma related variables. Levels of social support (with Oslo 3-Item Social Support Scale), disability (with WHO Disability Assessment Scale) were assessed. The presence of anxiety and depression was assessed using the Mini International Neuropsychiatric Interview (M.I.N.I) and asthma related quality of life was assessed with the Mini-Asthma Quality of Life Questionnaire (Mini-AQLQ). RESULTS: Of the 4 domains of Mini-AQLQ, the "environmental" domain has the lowest weighted mean score of 2.43 (SD = 1.64) while the "activity limitation" domain has the highest mean score of 4.74 (SD = 1.57). Poor asthma related QOL was independently associated with being unemployed (p = 0.028), poor social support (p = 0.002), nocturnal asthma (p = 0.046), clinically rated "severe asthma" (p = 0.002), patients rated "severe asthma" (p < 0.001), high level of disability (p < 0.001) and presence of Anxiety/Depression (p < 0.001). CONCLUSION: Our study has shown that psychological variables, disability, patients' subjective severity rating and social support are the most important factors independently associated with asthma related QOL. These factors should be considered in planning health care services or formulating a predictive intervention model.
BACKGROUND: This study aimed to assess the effect of psychological and other possible factors associated with poor health related quality of life (HRQOL) in outpatient with asthma in Lagos, Nigeria. METHODS:Patients (n = 201) recruited from the adult asthmaoutpatient clinic were assessed for sociodemographic and asthma related variables. Levels of social support (with Oslo 3-Item Social Support Scale), disability (with WHO Disability Assessment Scale) were assessed. The presence of anxiety and depression was assessed using the Mini International Neuropsychiatric Interview (M.I.N.I) and asthma related quality of life was assessed with the Mini-Asthma Quality of Life Questionnaire (Mini-AQLQ). RESULTS: Of the 4 domains of Mini-AQLQ, the "environmental" domain has the lowest weighted mean score of 2.43 (SD = 1.64) while the "activity limitation" domain has the highest mean score of 4.74 (SD = 1.57). Poor asthma related QOL was independently associated with being unemployed (p = 0.028), poor social support (p = 0.002), nocturnal asthma (p = 0.046), clinically rated "severe asthma" (p = 0.002), patients rated "severe asthma" (p < 0.001), high level of disability (p < 0.001) and presence of Anxiety/Depression (p < 0.001). CONCLUSION: Our study has shown that psychological variables, disability, patients' subjective severity rating and social support are the most important factors independently associated with asthma related QOL. These factors should be considered in planning health care services or formulating a predictive intervention model.
Authors: Stephen M Friedman; Howard Alper; Rafael E de la Hoz; Sukhminder Osahan; Mark R Farfel; James Cone Journal: Int J Environ Res Public Health Date: 2022-06-25 Impact factor: 4.614
Authors: Sabina Stanescu; Sarah E Kirby; Mike Thomas; Lucy Yardley; Ben Ainsworth Journal: NPJ Prim Care Respir Med Date: 2019-10-21 Impact factor: 2.871
Authors: Martin W Njoroge; Patrick Mjojo; Catherine Chirwa; Sarah Rylance; Rebecca Nightingale; Stephen B Gordon; Kevin Mortimer; Peter Burney; John Balmes; Jamie Rylance; Angela Obasi; Louis W Niessen; Graham Devereux Journal: EClinicalMedicine Date: 2021-10-18