| Literature DB >> 27990673 |
Michael Barton1, Suing Lockhart2, Robert Sidbury2, Richard Wang3, Heather Brandling-Bennett2.
Abstract
Trichodysplasia spinulosa (TS) is an uncommon skin disease characterized by a folliculocentric papular eruption and keratin spine formation, classically appearing on the central face and ears. It occurs in immunosuppressed patients and is linked to a viral etiology. Diagnostic tests including polymerase chain reaction (PCR) are available for detection of the TS-associated polyomavirus. Effective treatment options include topical cidofovir and oral valganciclovir. We present a case diagnosed using PCR with skin scrapings and treated using physical extraction of the keratin spicules. Significant improvement was noted, suggesting a safe, cost-effective treatment alternative.Entities:
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Year: 2016 PMID: 27990673 PMCID: PMC5788291 DOI: 10.1111/pde.13045
Source DB: PubMed Journal: Pediatr Dermatol ISSN: 0736-8046 Impact factor: 1.588