| Literature DB >> 27990577 |
Adeline Nyamathi1, Maria Ekstrand2, Elsa Heylen2, Padma Ramakrishna3, Kartik Yadav4, Sanjeev Sinha5, Angela Hudson6, Catherine L Carpenter4, Lenore Arab7.
Abstract
We conducted a cross-sectional examination of the physical and psychological factors related to ART adherence among a sample of 400 women living with HIV/AIDS in rural India. Interviewer-administered measures assessed adherence, internalized stigma, depressive symptoms, quality of life, food insecurity, health history and sociodemographic information. CD4 counts were measured using blood collected at screening. Findings revealed that adherence to ART was generally low, with 94% of women taking 50% or less of prescribed medication in past month. Multivariate analyses showed a non-linear association between numbers of self-reported opportunistic infections (OIs) in past 6 months (p = 0.016) and adherence, with adherence decreasing with each additional OI for 0-5 OIs. For those reporting more than 5 OIs, the association reversed direction, with increasing OIs beyond 5 associated with greater adherence.Entities:
Keywords: AIDS; India; Opportunistic infections; Women
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Year: 2018 PMID: 27990577 PMCID: PMC5476510 DOI: 10.1007/s10461-016-1631-3
Source DB: PubMed Journal: AIDS Behav ISSN: 1090-7165