Literature DB >> 2798756

Vasopressin reduces food intake in goats.

A H Meyer1, W Langhans, E Scharrer.   

Abstract

The effect of arginine vasopressin (VP) on cumulative food intake and meal pattern was tested in pygmy goats. VP injected intraperitoneally (I.P.) (0.75, 1.5 and 3.0 micrograms kg-1 body weight) appeared to reduce food intake in a dose-dependent manner by reducing the size of the first meal and by increasing the first intermeal interval (IMI). The hypophagic effect of VP was reversed by both a V1-receptor antagonist and an alpha-adrenergic antagonist. Exogenous VP (0.75 and 1.5 microgram kg-1 body weight I.P.) produced increases in plasma VP concentration which also may occur in stressful situations. VP might therefore be related to stress-induced anorexia.

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Year:  1989        PMID： 2798756     DOI： 10.1113/expphysiol.1989.sp003294

Source DB:  PubMed          Journal:  Q J Exp Physiol        ISSN： 0144-8757


  10 in total

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  10 in total

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