Blessed Winston A1, Debasis Das Adhikari2, Saibal Das1, Kaysina Vazhudhi1, Aniket Kumar1, Margaret Shanthi Fx1, Indira Agarwal3. 1. a Department of Pharmacology and Clinical Pharmacology , Christian Medical College , Vellore , Tamil Nadu , India. 2. b Paediatric Emergency, Department of Paediatrics , Christian Medical College , Vellore , Tamil Nadu , India. 3. c Child Health 2, Department of Paediatrics , Christian Medical College , Vellore , Tamil Nadu , India.
Abstract
OBJECTIVES: This study was performed to determine the incidence, demographic distribution, types and outcomes across various drug poisonings among children from south India. METHODS: This retrospective study included children less than 16 years who presented to the Pediatric Emergency Department with drug poisoning from the 1st of October 2004 to the 30th of September 2013. RESULTS: Out of the total 997 poisoning cases, 366 (36.71%) were contributed by drugs; mainly antiepileptics, central nervous system depressants, psychotropics, analgesic-antipyretics and natural drugs. Males and children of < 5 years were mostly affected. Although many children developed complications and required intensive care unit admissions, the total mortality rate was less than 1%. The incidence of drug poisoning showed a decreasing trend over the last 4 years. CONCLUSION: This study for the first time gives an elaborative insight into pediatric drug poisoning over a nine-year period from a Pediatric Emergency Department tertiary care center in south India.
OBJECTIVES: This study was performed to determine the incidence, demographic distribution, types and outcomes across various drug poisonings among children from south India. METHODS: This retrospective study included children less than 16 years who presented to the Pediatric Emergency Department with drug poisoning from the 1st of October 2004 to the 30th of September 2013. RESULTS: Out of the total 997 poisoning cases, 366 (36.71%) were contributed by drugs; mainly antiepileptics, central nervous system depressants, psychotropics, analgesic-antipyretics and natural drugs. Males and children of < 5 years were mostly affected. Although many children developed complications and required intensive care unit admissions, the total mortality rate was less than 1%. The incidence of drug poisoning showed a decreasing trend over the last 4 years. CONCLUSION: This study for the first time gives an elaborative insight into pediatric drug poisoning over a nine-year period from a Pediatric Emergency Department tertiary care center in south India.
Entities:
Keywords:
Drugs; children; poisoning; south India; toxicity
Authors: Machinary Puthenpurayil Jayakrishnan; Padinharath Krishnakumar; Madathil Govindaraj Geeta; Biju George Journal: Indian J Community Med Date: 2021-05-29