| Literature DB >> 27984921 |
Jorge Enrique Machado-Alba1, Andrés Gaviria-Mendoza1, Manuel Enrique Machado-Duque1, Laura Chica1.
Abstract
It is estimated that one-fifth of adult patients are treated with polypharmacy (five or more drugs) and the prevalence of this phenomenon in the elderly is even higher, ranging from 30% to 70%, even reaching 90% in residents of residential aged care facilities. Polypharmacy in the elderly increases the risk of adverse reactions, inappropriate prescriptions, drug interactions, number of hospitalizations, costs, and even death. In a recent systematic review, the authors proposed defining deprescribing as 'the process of withdrawal of inappropriate medication supervised by a health care professional with the goal of managing polypharmacy and improving outcomes'.Entities:
Keywords: Deprescriptions; pharmacoepidemiology; pharmacovigilance; polypharmacy
Mesh:
Year: 2016 PMID: 27984921 DOI: 10.1080/14740338.2017.1273347
Source DB: PubMed Journal: Expert Opin Drug Saf ISSN: 1474-0338 Impact factor: 4.250