Literature DB >> 27984246

The Hypothalamic-Pituitary-Adrenal Axis and Anesthetics: A Review.

Emmanuel Besnier1, Thomas Clavier, Vincent Compere.   

Abstract

The hypothalamic-pituitary-adrenal (HPA) axis is essential for human adaptation to stress. However, many anesthetic agents may interfere with the activity of this axis. Although etomidate is known for its suppressive effect on HPA axis function, in vitro evidence suggests that many other drugs used in anesthesia care may also interfere with HPA activity. In this review, we discuss the mechanisms by which all HPA axis activity may be altered during anesthesia and critical care and focus on the impact of hypnotic and analgesic drugs.

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Year:  2017        PMID： 27984246     DOI： 10.1213/ANE.0000000000001580

Source DB:  PubMed          Journal:  Anesth Analg        ISSN： 0003-2999            Impact factor:   5.108


  7 in total

Review 1.  General anesthesia bullies the gut: a toxic relationship with dysbiosis and cognitive dysfunction.

Authors:  Lidan Liu; Lihua Shang; Dongxue Jin; Xiuying Wu; Bo Long
Journal:  Psychopharmacology (Berl)       Date:  2022-02-21       Impact factor: 4.530

Review 2.  Intrinsic Connectivity Networks of Glutamate-Mediated Antidepressant Response: A Neuroimaging Review.

Authors:  Ilya Demchenko; Vanessa K Tassone; Sidney H Kennedy; Katharine Dunlop; Venkat Bhat
Journal:  Front Psychiatry       Date:  2022-05-26       Impact factor: 5.435

Review 3.  Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes.

Authors:  Koichi Yuki; Lifei Hou; Miho Shibamura-Fujiogi; Sophia Koutsogiannaki; Sulpicio G Soriano
Journal:  Clin Immunol       Date:  2020-11-17       Impact factor: 3.969

4.  Pharmacodynamics and Pharmacokinetics of HSK3486, a Novel 2,6-Disubstituted Phenol Derivative as a General Anesthetic.

Authors:  Juan Liao; Meiting Li; Chaoli Huang; Yan Yu; Yashu Chen; Jiaqi Gan; Jie Xiao; Guilin Xiang; Xizhi Ding; Rong Jiang; Peng Li; Mengchang Yang
Journal:  Front Pharmacol       Date:  2022-02-03       Impact factor: 5.810

5.  Developing a prediction model for estimating adrenocorticotropic hormone changes in patients undergoing scheduled open hepatectomy.

Authors:  Yu Guan; Jie Tang; Jiali Yu; Yiqi Zhu; Ailun Li; Fang Fang; Jing Cang
Journal:  Ann Transl Med       Date:  2022-06

6.  Perioperative serum cortisol levels in ACTH sufficient and ACTH deficient patients during transsphenoidal surgery of pituitary adenoma.

Authors:  Henrik Borg; Peter Siesjö; Babar Kahlon; Sigridur Fjalldal; Eva Marie Erfurth
Journal:  Endocrine       Date:  2018-07-02       Impact factor: 3.633

7.  Dynamics and prognostic value of the hypothalamus-pituitary-adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study.

Authors:  Ilse Vanhorebeek; Greet Van den Berghe; An Jacobs; Inge Derese; Sarah Vander Perre; Pieter J Wouters; Sascha Verbruggen; Jaak Billen; Pieter Vermeersch; Gonzalo Garcia Guerra; Koen Joosten
Journal:  Intensive Care Med       Date:  2019-11-11       Impact factor: 17.440
  7 in total

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