Literature DB >> 2798363

Preparation of 4-halo-3-hydroxyanthranilates and demonstration of their inhibition of 3-hydroxyanthranilate oxygenase activity in rat and human brain tissue.

W P Todd1, B K Carpenter, R Schwarcz.   

Abstract

The chemical syntheses of 4-fluoro-, 4-chloro-, and 4-bromo-3-hydroxyanthranilic acids are described. Their actions as inhibitors of 3-hydroxyanthranilate oxygenase in cell-free homogenates from rat and human brain and in rat brain slices are presented.

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Year:  1989        PMID： 2798363     DOI： 10.1080/10826068908544905

Source DB:  PubMed          Journal:  Prep Biochem        ISSN： 0032-7484


  3 in total

1.  Excitotoxicity of quinolinic acid: modulation by endogenous antagonists.

Authors:  K H Jhamandas; R J Boegman; R J Beninger; A F Miranda; K A Lipic
Journal:  Neurotox Res       Date:  2000       Impact factor: 3.911

2.  Structural and Mechanistic Insights into the Pseudomonas fluorescens 2-Nitrobenzoate 2-Nitroreductase NbaA.

Authors:  Yong-Hak Kim; Wooseok Song; Jin-Sik Kim; Li Jiao; Kangseok Lee; Nam-Chul Ha
Journal:  Appl Environ Microbiol       Date:  2015-05-29       Impact factor: 4.792

3.  Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

Authors:  Margaret M Lowe; Jeff E Mold; Bittoo Kanwar; Yong Huang; Alexander Louie; Michael P Pollastri; Cuihua Wang; Gautam Patel; Diana G Franks; Jennifer Schlezinger; David H Sherr; Allen E Silverstone; Mark E Hahn; Joseph M McCune
Journal:  PLoS One       Date:  2014-02-03       Impact factor: 3.240
  3 in total

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