| Literature DB >> 2798186 |
S Kunathai1, G F Sholler, J M Celermajer, M O'Halloran, T B Cartmill, G R Nunn.
Abstract
Thiocyanate levels, an indicator of nitroprusside toxicity, were studied in 22 children after repair of structural heart disease during cardiopulmonary bypass. At the total dose (2.6 +/- 2.3 mg/kg) and time (34.4 +/- 19 h) ranges of this study, no evidence of toxicity was detected, despite this total dose exceeding recommended maximum in some patients. Nitroprusside infusion, as described, in children with normal hepatic and renal function is safe and may not warrant routine assessment of thiocyanate levels.Entities:
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Year: 1989 PMID: 2798186 DOI: 10.1007/BF02081673
Source DB: PubMed Journal: Pediatr Cardiol ISSN: 0172-0643 Impact factor: 1.655