Literature DB >> 2798186

Nitroprusside in children after cardiopulmonary bypass: a study of thiocyanate toxicity.

S Kunathai1, G F Sholler, J M Celermajer, M O'Halloran, T B Cartmill, G R Nunn.   

Abstract

Thiocyanate levels, an indicator of nitroprusside toxicity, were studied in 22 children after repair of structural heart disease during cardiopulmonary bypass. At the total dose (2.6 +/- 2.3 mg/kg) and time (34.4 +/- 19 h) ranges of this study, no evidence of toxicity was detected, despite this total dose exceeding recommended maximum in some patients. Nitroprusside infusion, as described, in children with normal hepatic and renal function is safe and may not warrant routine assessment of thiocyanate levels.

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Year:  1989        PMID: 2798186     DOI: 10.1007/BF02081673

Source DB:  PubMed          Journal:  Pediatr Cardiol        ISSN: 0172-0643            Impact factor:   1.655


  19 in total

1.  The determination of thiocyanate in blood serum.

Authors:  R G Bowler
Journal:  Biochem J       Date:  1944       Impact factor: 3.857

2.  Sodium nitroprusside in idiopathic respiratory distress syndrome.

Authors:  T R Abbott; G J Rews; D Dickinson; G Reynolds; D Lord
Journal:  Br Med J       Date:  1978-04-29

3.  The toxicity of sodium nitroprusside.

Authors:  D G McDowall; N P Keaney; J M Turner; J R Lane; Y Okuda
Journal:  Br J Anaesth       Date:  1974-05       Impact factor: 9.166

4.  Treatment of refractory heart failure with infusion of nitroprusside.

Authors:  N H Guiha; J N Cohn; E Mikulic; J A Franciosa; C J Limas
Journal:  N Engl J Med       Date:  1974-09-19       Impact factor: 91.245

5.  Human myocardial performance during surgical treatment of cardiac defects.

Authors:  G Benzing; J Helmsworth; J Stockert; S Kaplan
Journal:  J Thorac Cardiovasc Surg       Date:  1970-06       Impact factor: 5.209

Review 6.  Vasodilator therapy of cardiac failure: (first of two parts).

Authors:  J N Cohn; J A Franciosa
Journal:  N Engl J Med       Date:  1977-07-07       Impact factor: 91.245

7.  Early use of sodium nitroprusside in respiratory distress syndrome.

Authors:  D W Beverley; C A Hughes; D P Davies; M J Harran; D A Ducker
Journal:  Arch Dis Child       Date:  1979-05       Impact factor: 3.791

8.  Sodium nitroprusside: pharmacology, toxicology and therapeutics.

Authors:  J H Tinker; J D Michenfelder
Journal:  Anesthesiology       Date:  1976-09       Impact factor: 7.892

9.  Cyanide and thiocyanate concentrations following sodium nitroprusside infusion in man.

Authors:  C J Vesey; P V Cole; P J Simpson
Journal:  Br J Anaesth       Date:  1976-07       Impact factor: 9.166

10.  Vasodilator therapy for congestive heart failure.

Authors:  T R Dillon; G G Janos; R A Meyer; G Benzing; S Kaplan
Journal:  J Pediatr       Date:  1980-04       Impact factor: 4.406

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  3 in total

Review 1.  Drug treatment of hypertensive crisis in children.

Authors:  Christopher A Thomas
Journal:  Paediatr Drugs       Date:  2011-10-01       Impact factor: 3.022

2.  Elevated carboxyhemoglobin associated with sodium nitroprusside treatment.

Authors:  Jesús López-Herce; Raúl Borrego; Amaya Bustinza; Angel Carrillo
Journal:  Intensive Care Med       Date:  2005-07-22       Impact factor: 17.440

3.  Monitoring cyanide and thiocyanate concentrations during infusion of sodium nitroprusside in children.

Authors:  J G Linakis; P G Lacouture; A Woolf
Journal:  Pediatr Cardiol       Date:  1991-10       Impact factor: 1.655

  3 in total

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