Renal cell carcinoma and hematological malignancies.

We read with great interest the article entitle “Chronic lymphocytic lymphoma and concomitant renal cell carcinoma (Clear Cell Type): Review of the literature”, written by Uz et al. [1] and published in a recent issue of your journal. Here, we would like to emphasize some points about this review of the literature.

Previously, we also reported 3 cases with hematological malignancies and renal cell carcinoma (RCC) [2,3]. In our series, all patients had lymphoproliferative malignancies. Other than as specified in this article, we presented a 82-year-old female patient with coincidence of chronic lymphocytic lymphoma (CLL) and RCC [2]. Coincidence of CLL and RCC may be synchronous or asynchronous. Beisland et al.’s [4] study showed an incidence of 3.7% of synchronous tumors with RCC. Our patient had synchronous malignencies. The other case was a 53-year-old male patient diagnosed with RCC 4 years prior to Hodgkin's disease (Ann-Arbor, stage II-B) [3]. And, the third was 69-year-old male patient, diagnosed with multiple myeloma (IgG, κ, stage II-A) and RCC of left nephrectomy specimens, synchronously [3]. Interestingly, unlike our patient, Choueiri et al. reported case series of MM and RCC on the right side with right renal involvement except for one [5].