Literature DB >> 27979864

Metformin: treating the cause of Fanconi anemia?

Gerry P Crossan1.   

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Year:  2016        PMID： 27979864      PMCID： PMC5305048          DOI： 10.1182/blood-2016-11-748129

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  9 in total

1.  Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.

Authors:  Frédéric Langevin; Gerry P Crossan; Ivan V Rosado; Mark J Arends; Ketan J Patel
Journal:  Nature       Date:  2011-07-06       Impact factor: 49.962

2.  Functional analysis of the putative peroxidase domain of FANCA, the Fanconi anemia complementation group A protein.

Authors:  J Ren; H Youssoufian
Journal:  Mol Genet Metab       Date:  2001-01       Impact factor: 4.797

3.  Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Authors:  Dagmar Walter; Amelie Lier; Anja Geiselhart; Frederic B Thalheimer; Sina Huntscha; Mirko C Sobotta; Bettina Moehrle; David Brocks; Irem Bayindir; Paul Kaschutnig; Katja Muedder; Corinna Klein; Anna Jauch; Timm Schroeder; Hartmut Geiger; Tobias P Dick; Tim Holland-Letz; Peter Schmezer; Steven W Lane; Michael A Rieger; Marieke A G Essers; David A Williams; Andreas Trumpp; Michael D Milsom
Journal:  Nature       Date:  2015-02-18       Impact factor: 49.962

4.  Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice.

Authors:  Qing-Shuo Zhang; Weiliang Tang; Matthew Deater; Ngoc Phan; Andrea N Marcogliese; Hui Li; Muhsen Al-Dhalimy; Angela Major; Susan Olson; Raymond J Monnat; Markus Grompe
Journal:  Blood       Date:  2016-10-18       Impact factor: 22.113

5.  Role of AMP-activated protein kinase in mechanism of metformin action.

Authors:  G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

6.  Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.

Authors:  Ashley N Kamimae-Lanning; Natalya A Goloviznina; Peter Kurre
Journal:  Blood       Date:  2013-01-11       Impact factor: 22.113

7.  Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.

Authors:  John R Ridpath; Ayumi Nakamura; Keizo Tano; April M Luke; Eiichiro Sonoda; Hiroshi Arakawa; Jean-Marie Buerstedde; David A F Gillespie; Julian E Sale; Mitsuyoshi Yamazoe; Douglas K Bishop; Minoru Takata; Shunichi Takeda; Masami Watanabe; James A Swenberg; Jun Nakamura
Journal:  Cancer Res       Date:  2007-12-01       Impact factor: 12.701

8.  The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair.

Authors:  Wendy L Bridge; Cassandra J Vandenberg; Roger J Franklin; Kevin Hiom
Journal:  Nat Genet       Date:  2005-08-21       Impact factor: 38.330

9.  Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.

Authors:  Juan I Garaycoechea; Gerry P Crossan; Frederic Langevin; Maria Daly; Mark J Arends; Ketan J Patel
Journal:  Nature       Date:  2012-08-26       Impact factor: 49.962
  9 in total

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