Literature DB >> 27978748

Assembly of Polysubstituted Maleimides via Palladium-Catalyzed Cyclization Reaction of Alkynes with Isocyanides.

Weigao Hu1, Jia Zheng1, Jianxiao Li1, Bifu Liu1, Wanqing Wu1, Haiyang Liu1, Huanfeng Jiang1.   

Abstract

An efficient and convenient palladium-catalyzed cyclization reaction of alkynes with isocyanides is described herein. This protocol allows the practical synthesis of many valuable polysubstituted maleimide derivatives after hydrolysis with a broad scope of substrates and mild reaction conditions. C-C, C═O, and C-N bonds were constructed in this transformation with isocyanide serving as both C and N sources.

Entities:  

Year:  2016        PMID： 27978748     DOI： 10.1021/acs.joc.6b02227

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

2.  Synthesis and Structural Study of Amidrazone Derived Pyrrole-2,5-Dione Derivatives: Potential Anti-Inflammatory Agents.

Authors:  Renata Paprocka; Leszek Pazderski; Liliana Mazur; Małgorzata Wiese-Szadkowska; Jolanta Kutkowska; Michalina Nowak; Anna Helmin-Basa
Journal:  Molecules       Date:  2022-04-30       Impact factor: 4.411

Review 3.  Recent Advances in Palladium-Catalyzed Isocyanide Insertions.

Authors:  Jurriën W Collet; Thomas R Roose; Bram Weijers; Bert U W Maes; Eelco Ruijter; Romano V A Orru
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411
  3 in total

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