Literature DB >> 27976457

Global Health and Emergency Care: Overcoming Clinical Research Barriers.

Adam C Levine1, Meagan A Barry2, Pooja Agrawal3, Herbert C Duber4, Mary P Chang5, Joy M Mackey2, Bhakti Hansoti6.   

Abstract

OBJECTIVES: There are many barriers impeding the conduct of high-quality emergency care research, particularly in low- and middle-income countries. Several of these barriers were originally outlined in 2013 as part of the Academic Emergency Medicine Global Health and Emergency Care Consensus Conference. This paper seeks to establish a broader consensus on the barriers to emergency care research globally and proposes a comprehensive array of new recommendations to overcome these barriers.
METHODS: An electronic survey was conducted of a purposive sample of global emergency medicine research experts from around the world to describe the major challenges and solutions to conducting emergency care research in low-resource settings and rank them by importance. The Global Emergency Medicine Think Tank Clinical Research Working Group at the Society for Academic Emergency Medicine 2016 Annual Meeting utilized a modified Delphi technique for consensus-based decision making to categorize and expand upon these barriers and develop a comprehensive array of proposed solutions.
RESULTS: The working group identified four broad categories of barriers to conducting emergency care research globally, including 1) the limited availability of research personnel, particularly those with prior research training; 2) logistic barriers and lack of standardization of data collection; 3) ethical barriers to conducting research in resource-limited settings, particularly when no local institutional review board is available; and 4) the relative dearth of funding for global emergency care research. Proposed solutions included building a diverse and interdisciplinary research team structured to promote mentorship of junior researchers, utilizing local research assistants or technologic tools such as telemedicine for language translation, making use of new tools such as mobile health (mHealth) to standardize and streamline data collection, identifying alternatives to local institutional review board approval and the use of community consent when appropriate, and increased advocacy for global emergency care research funding.
CONCLUSIONS: Significant barriers to the conduct of high-quality global emergency care research persist, and innovative strategies need to be adopted to promote and grow the field of global emergency care research. This paper provides a global consensus on the most important barriers identified, as well as recommendations for cost-effective strategies for overcoming these barriers with the overall goal of promoting high-quality research and improving emergency care worldwide.
© 2016 by the Society for Academic Emergency Medicine.

Mesh:

Year:  2017        PMID: 27976457     DOI: 10.1111/acem.13142

Source DB:  PubMed          Journal:  Acad Emerg Med        ISSN: 1069-6563            Impact factor:   3.451


  6 in total

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Journal:  Front Genet       Date:  2022-06-27       Impact factor: 4.772

2.  Processes of consent in research for adults with impaired mental capacity nearing the end of life: systematic review and transparent expert consultation (MORECare_Capacity statement).

Authors:  C J Evans; E Yorganci; P Lewis; J Koffman; K Stone; I Tunnard; B Wee; W Bernal; M Hotopf; I J Higginson
Journal:  BMC Med       Date:  2020-07-22       Impact factor: 8.775

3.  Harnessing Clinical Trial Capacity to Mitigate Zoonotic Diseases: The Role of Expert Scientists in Ethiopia.

Authors:  Senait Belay; Mirutse Giday; Tsegahun Manyazewal
Journal:  Front Public Health       Date:  2021-04-01

4.  The ethical considerations for emergency care research in low- and middle-income countries: A scoping review of the published literature.

Authors:  Sarah Hirner; Colleen Saunders; Willem Stassen
Journal:  Afr J Emerg Med       Date:  2022-01-14

5.  White Paper on Early Critical Care Services in Low Resource Settings.

Authors:  Lia I Losonczy; Alfred Papali; Sean Kivlehan; Emilie J Calvello Hynes; Georgina Calderon; Adam Laytin; Vanessa Moll; Ahmed Al Hazmi; Mohammed Alsabri; Diptesh Aryal; Vincent Atua; Torben Becker; Nicole Benzoni; Enrico Dippenaar; Edrist Duneant; Biruk Girma; Naomi George; Preeti Gupta; Michael Jaung; Bonaventure Hollong; Diulu Kabongo; Rebecca J Kruisselbrink; Dennis Lee; Augusto Maldonado; Jesse May; Maxwell Osei-Ampofo; Yasein Omer Osman; Christian Owoo; Shada A Rouhani; Hendry Sawe; Daniel Schnorr; Gentle S Shrestha; Aparajita Sohoni; Menbeu Sultan; Andrea G Tenner; Hanan Yusuf; Neill K Adhikari; Srinvas Murthy; Niranjan Kissoon; John Marshall; Abdo Khoury; Abdelouahab Bellou; Lee Wallis; Teri Reynolds
Journal:  Ann Glob Health       Date:  2021-11-03       Impact factor: 2.462

6.  Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research.

Authors:  Sophie Bockhold; Shane J Foley; Louise A Rainford; Riccardo Corridori; Annika Eberstein; Christoph Hoeschen; Mark W Konijnenberg; Susan Molyneux-Hodgson; Graciano Paulo; Joana Santos; Jonathan P McNulty
Journal:  J Transl Med       Date:  2022-03-18       Impact factor: 5.531

  6 in total

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