Literature DB >> 27966686

A microchip electrophoresis-based fluorescence signal amplification strategy for highly sensitive detection of biomolecules.

Yingfeng Qin1, Liangliang Zhang1, Shuting Li1, Jingjin Zhao1, Yong Huang1, Shulin Zhao1, Yi-Ming Liu2.   

Abstract

We have developed a microchip electrophoresis (MCE)-based fluorescence signal amplification strategy as a universal MCE method for the detection of trace biomolecules. This strategy exhibits high sensitivity and specificity for target molecules, and has been applied for the detection of interferon-gamma (IFN-γ) in human plasma with satisfactory results.

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Year:  2016        PMID： 27966686      PMCID： PMC5446791          DOI： 10.1039/c6cc08911a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  24 in total

1.  Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays.

Authors:  Yong Huang; Shulin Zhao; Zhen-Feng Chen; Ming Shi; Hong Liang
Journal:  Chem Commun (Camb)       Date:  2012-06-22       Impact factor: 6.222

2.  Highly sensitive and selective detection of miRNA: DNase I-assisted target recycling using DNA probes protected by polydopamine nanospheres.

Authors:  Yi Xie; Xiaoyan Lin; Yishun Huang; Rujun Pan; Zhi Zhu; Leiji Zhou; Chaoyong James Yang
Journal:  Chem Commun (Camb)       Date:  2015-01-02       Impact factor: 6.222

3.  Microchip zone electrophoresis for high-throughput analysis of monoclonal antibody charge variants.

Authors:  Tobias D Wheeler; Jing Lucy Sun; Sina Pleiner; Holger Geier; Philine Dobberthien; Joey Studts; Rajendra Singh; Bahram Fathollahi
Journal:  Anal Chem       Date:  2014-05-13       Impact factor: 6.986

4.  Highly sensitive and homogeneous detection of membrane protein on a single living cell by aptamer and nicking enzyme assisted signal amplification based on microfluidic droplets.

Authors:  Lu Li; Qian Wang; Jie Feng; Lili Tong; Bo Tang
Journal:  Anal Chem       Date:  2014-05-08       Impact factor: 6.986

5.  Beyond "turn-on" readout: from zero background to signal amplification by combination of magnetic separation and plasmon enhanced fluorescence.

Authors:  Suqin Gong; Yunsheng Xia
Journal:  Chem Commun (Camb)       Date:  2016-07-11       Impact factor: 6.222

Review 6.  Chemical analysis of single cells.

Authors:  Yuqing Lin; Raphaël Trouillon; Gulnara Safina; Andrew G Ewing
Journal:  Anal Chem       Date:  2011-04-28       Impact factor: 6.986

7.  Continuous analysis of dye-loaded, single cells on a microfluidic chip.

Authors:  K Scott Phillips; Hsuan Hong Lai; Emily Johnson; Christopher E Sims; Nancy L Allbritton
Journal:  Lab Chip       Date:  2011-02-16       Impact factor: 6.799

8.  Chemiluminescence resonance energy transfer-based detection for microchip electrophoresis.

Authors:  Shulin Zhao; Yong Huang; Ming Shi; Rongjun Liu; Yi-Ming Liu
Journal:  Anal Chem       Date:  2010-03-01       Impact factor: 6.986

9.  Polymeric microchip for the simultaneous determination of anions and cations by hydrodynamic injection using a dual-channel sequential injection microchip electrophoresis system.

Authors:  Adam J Gaudry; Yi Heng Nai; Rosanne M Guijt; Michael C Breadmore
Journal:  Anal Chem       Date:  2014-03-17       Impact factor: 6.986

10.  Sensitive, selective analysis of selenium oxoanions using microchip electrophoresis with contact conductivity detection.

Authors:  Scott D Noblitt; Lucian C Staicu; Christopher J Ackerson; Charles S Henry
Journal:  Anal Chem       Date:  2014-07-29       Impact factor: 6.986
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  3 in total

1.  Microfluidic electrophoretic non-enzymatic kanamycin assay making use of a stirring bar functionalized with gold-labeled aptamer, of a fluorescent DNA probe, and of signal amplification via hybridization chain reaction.

Authors:  Kai Zhang; Ning Gan; Futao Hu; Xixue Chen; Tianhua Li; Jinxuan Cao
Journal:  Mikrochim Acta       Date:  2018-02-17       Impact factor: 5.833

Review 2.  Recent Advances in Aptasensor for Cytokine Detection: A Review.

Authors:  Jinmyeong Kim; Seungwoo Noh; Jeong Ah Park; Sang-Chan Park; Seong Jun Park; Jin-Ho Lee; Jae-Hyuk Ahn; Taek Lee
Journal:  Sensors (Basel)       Date:  2021-12-20       Impact factor: 3.576

3.  Biosensing bacterial 16S rDNA by microchip electrophoresis combined with a CRISPR system based on real-time crRNA/Cas12a formation.

Authors:  Feifei Luo; Xing Geng; Zhi Li; Ge Dai; Zhaohui Chu; Pingang He; Fan Zhang; Qingjiang Wang
Journal:  RSC Adv       Date:  2022-08-10       Impact factor: 4.036
  3 in total

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