Literature DB >> 27965988

Single molecule based SNP detection using designed DNA carriers and solid-state nanopores.

Jinglin Kong1, Jinbo Zhu1, Ulrich F Keyser1.   

Abstract

Single nucleotide polymorphisms (SNPs) play a crucial role as molecular markers in medical and diagnostic application. We demonstrate a nanopore based method for SNP detection at the single molecule level. Designed DNA carriers are used to distinguish DNA strands containing only one single base difference and follow strand displacement kinetics.

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Year:  2016        PMID： 27965988     DOI： 10.1039/c6cc08621g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derived Nucleic Acid Sequence.

Authors:  Maryam Imani Nejad; Ruicheng Shi; Xinyue Zhang; Li-Qun Gu; Kent S Gates
Journal:  Chembiochem       Date:  2017-05-26       Impact factor: 3.164

2.  Nanolock-Nanopore Facilitated Digital Diagnostics of Cancer Driver Mutation in Tumor Tissue.

Authors:  Yong Wang; Kai Tian; Ruicheng Shi; Amy Gu; Michael Pennella; Lindsey Alberts; Kent S Gates; Guangfu Li; Hongxin Fan; Michael X Wang; Li-Qun Gu
Journal:  ACS Sens       Date:  2017-07-05       Impact factor: 7.711

Review 3.  What is the potential of nanolock- and nanocross-nanopore technology in cancer diagnosis?

Authors:  Li-Qun Gu; Kent S Gates; Michael X Wang; Guangfu Li
Journal:  Expert Rev Mol Diagn       Date:  2017-12-01       Impact factor: 5.225

4.  Entropic Trapping of DNA with a Nanofiltered Nanopore.

Authors:  Michelle H Lam; Kyle Briggs; Konstantinos Kastritis; Martin Magill; Gregory R Madejski; James L McGrath; Hendrick W de Haan; Vincent Tabard-Cossa
Journal:  ACS Appl Nano Mater       Date:  2019-06-19

5.  Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations.

Authors:  Kai Tian; Xiaowei Chen; Binquan Luan; Prashant Singh; Zhiyu Yang; Kent S Gates; Mengshi Lin; Azlin Mustapha; Li-Qun Gu
Journal:  ACS Nano       Date:  2018-04-23       Impact factor: 15.881

6.  Split G-Quadruplexes Enhance Nanopore Signals for Simultaneous Identification of Multiple Nucleic Acids.

Authors:  Jinbo Zhu; Filip Bošković; Ulrich F Keyser
Journal:  Nano Lett       Date:  2022-06-07       Impact factor: 12.262

7.  FeII4L4 Tetrahedron Binds to Nonpaired DNA Bases.

Authors:  Jinbo Zhu; Cally J E Haynes; Marion Kieffer; Jake L Greenfield; Ryan D Greenhalgh; Jonathan R Nitschke; Ulrich F Keyser
Journal:  J Am Chem Soc       Date:  2019-07-11       Impact factor: 15.419

8.  Lifetime of glass nanopores in a PDMS chip for single-molecule sensing.

Authors:  Mohammed F Alawami; Filip Bošković; Jinbo Zhu; Kaikai Chen; Sarah E Sandler; Ulrich F Keyser
Journal:  iScience       Date:  2022-04-04

Review 9.  Application of Nanotechnology for Sensitive Detection of Low-Abundance Single-Nucleotide Variations in Genomic DNA: A Review.

Authors:  Mahwash Mukhtar; Saman Sargazi; Mahmood Barani; Henning Madry; Abbas Rahdar; Magali Cucchiarini
Journal:  Nanomaterials (Basel)       Date:  2021-05-24       Impact factor: 5.076

10.  Detection of CRISPR-dCas9 on DNA with Solid-State Nanopores.

Authors:  Wayne Yang; Laura Restrepo-Pérez; Michel Bengtson; Stephanie J Heerema; Anthony Birnie; Jaco van der Torre; Cees Dekker
Journal:  Nano Lett       Date:  2018-09-13       Impact factor: 11.189
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