Literature DB >> 27960620

The GoSlo family of BK channel activators: A no-go for γ subunits?

Teresa Giraldez1.   

Abstract

Keywords:  BK channels; calcium; electrophysiology; excitability; ion channels; regulatory subunits; structure-function; voltage

Mesh：

Substances：

Year:  2016        PMID： 27960620      PMCID： PMC5398587          DOI： 10.1080/19336950.2016.1263136

Source DB:  PubMed          Journal:  Channels (Austin)        ISSN： 1933-6950            Impact factor:   2.581


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  8 in total

1.  Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels.

Authors:  Subhrangsu Roy; Roddy J Large; Adebola Morayo Akande; Aravind Kshatri; Tim I Webb; Carmen Domene; Gerard P Sergeant; Noel G McHale; Keith D Thornbury; Mark A Hollywood
Journal:  Eur J Med Chem       Date:  2014-02-03       Impact factor: 6.514

Review 2.  Molecular Determinants of BK Channel Functional Diversity and Functioning.

Authors:  Ramon Latorre; Karen Castillo; Willy Carrasquel-Ursulaez; Romina V Sepulveda; Fernando Gonzalez-Nilo; Carlos Gonzalez; Osvaldo Alvarez
Journal:  Physiol Rev       Date:  2017-01       Impact factor: 37.312

Review 3.  The BK channel: a vital link between cellular calcium and electrical signaling.

Authors:  Brad S Rothberg
Journal:  Protein Cell       Date:  2012-09-21       Impact factor: 14.870

4.  Differential efficacy of GoSlo-SR compounds on BKα and BKαγ1-4 channels.

Authors:  Aravind S Kshatri; Qin Li; Jiusheng Yan; Roddy J Large; Gerard P Sergeant; Noel G McHale; Keith D Thornbury; Mark A Hollywood
Journal:  Channels (Austin)       Date:  2016-07-20       Impact factor: 2.581

5.  LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium.

Authors:  Jiusheng Yan; Richard W Aldrich
Journal:  Nature       Date:  2010-07-07       Impact factor: 49.962

6.  BK potassium channel modulation by leucine-rich repeat-containing proteins.

Authors:  Jiusheng Yan; Richard W Aldrich
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

Review 7.  BK channel activators and their therapeutic perspectives.

Authors:  Bo H Bentzen; Søren-Peter Olesen; Lars C B Rønn; Morten Grunnet
Journal:  Front Physiol       Date:  2014-10-09       Impact factor: 4.566

8.  Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gating.

Authors:  Vivian Gonzalez-Perez; Xiao-Ming Xia; Christopher J Lingle
Journal:  Nat Commun       Date:  2015-09-21       Impact factor: 14.919
  8 in total

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