Literature DB >> 27960081

To PFKFB3 or Not to PFKFB3, That Is the Question.

Cristina Branco1, Randall S Johnson2.   

Abstract

In this issue of Cancer Cell, Cantelmo et al. describe how reduction of PFKFB3 enzyme activity can promote vascular normalization. The authors show in turn how this affects vascular permeability and can ultimately improve the efficacy of chemotherapeutic agents.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27960081     DOI: 10.1016/j.ccell.2016.11.007

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  2 in total

1.  Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming.

Authors:  Jia Liu; Ze-Xian Liu; Qi-Nian Wu; Yun-Xin Lu; Chau-Wei Wong; Lei Miao; Yun Wang; Zixian Wang; Ying Jin; Ming-Ming He; Chao Ren; De-Shen Wang; Dong-Liang Chen; Heng-Ying Pu; Lin Feng; Bo Li; Dan Xie; Mu-Sheng Zeng; Peng Huang; Aifu Lin; Dongxin Lin; Rui-Hua Xu; Huai-Qiang Ju
Journal:  Nat Commun       Date:  2020-03-20       Impact factor: 14.919

2.  Mir-488 alleviates chemoresistance and glycolysis of colorectal cancer by targeting PFKFB3.

Authors:  Xiaojing Deng; Dapeng Li; Xiquan Ke; Qizhi Wang; Shanjun Yan; Yongju Xue; Qiangwu Wang; Hailun Zheng
Journal:  J Clin Lab Anal       Date:  2020-09-29       Impact factor: 2.352

  2 in total

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