Literature DB >> 27959727

Thresholds for Abdominal Aortic Aneurysm Repair in England and the United States.

Alan Karthikesalingam1, Alberto Vidal-Diez1, Peter J Holt1, Ian M Loftus1, Marc L Schermerhorn1, Peter A Soden1, Bruce E Landon1, Matthew M Thompson1.   

Abstract

BACKGROUND: Thresholds for repair of abdominal aortic aneurysms vary considerably among countries.
METHODS: We examined differences between England and the United States in the frequency of aneurysm repair, the mean aneurysm diameter at the time of the procedure, and rates of aneurysm rupture and aneurysm-related death. Data on the frequency of repair of intact (nonruptured) abdominal aortic aneurysms, in-hospital mortality among patients who had undergone aneurysm repair, and rates of aneurysm rupture during the period from 2005 through 2012 were extracted from the Hospital Episode Statistics database in England and the U.S. Nationwide Inpatient Sample. Data on the aneurysm diameter at the time of repair were extracted from the U.K. National Vascular Registry (2014 data) and from the U.S. National Surgical Quality Improvement Program (2013 data). Aneurysm-related mortality during the period from 2005 through 2012 was determined from data obtained from the Centers for Disease Control and Prevention and the U.K. Office of National Statistics. Data were adjusted with the use of direct standardization or conditional logistic regression for differences between England and the United States with respect to population age and sex.
RESULTS: During the period from 2005 through 2012, a total of 29,300 patients in England and 278,921 patients in the United States underwent repair of intact abdominal aortic aneurysms. Aneurysm repair was less common in England than in the United States (odds ratio, 0.49; 95% confidence interval [CI], 0.48 to 0.49; P<0.001), and aneurysm-related death was more common in England than in the United States (odds ratio, 3.60; 95% CI, 3.55 to 3.64; P<0.001). Hospitalization due to an aneurysm rupture occurred more frequently in England than in the United States (odds ratio, 2.23; 95% CI, 2.19 to 2.27; P<0.001), and the mean aneurysm diameter at the time of repair was larger in England (63.7 mm vs. 58.3 mm, P<0.001).
CONCLUSIONS: We found a lower rate of repair of abdominal aortic aneurysms and a larger mean aneurysm diameter at the time of repair in England than in the United States and lower rates of aneurysm rupture and aneurysm-related death in the United States than in England. (Funded by the Circulation Foundation and others.).

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Year:  2016        PMID: 27959727      PMCID: PMC5177793          DOI: 10.1056/NEJMoa1600931

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  19 in total

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Authors:  F L Moll; J T Powell; G Fraedrich; F Verzini; S Haulon; M Waltham; J A van Herwaarden; P J E Holt; J W van Keulen; B Rantner; F J V Schlösser; F Setacci; J-B Ricco
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2.  The rationale for lowering the size threshold in elective endovascular repair of abdominal aortic aneurysm.

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3.  Regional Differences in Case Mix and Peri-operative Outcome After Elective Abdominal Aortic Aneurysm Repair in the Vascunet Database.

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4.  Comparison of surveillance versus aortic endografting for small aneurysm repair (CAESAR): results from a randomised trial.

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7.  Effect of endovascular aneurysm repair on the volume-outcome relationship in aneurysm repair.

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8.  The impact of endovascular aneurysm repair on mortality for elective abdominal aortic aneurysm repair in England and the United States.

Authors:  Alan Karthikesalingam; Peter J Holt; Alberto Vidal-Diez; Sandeep S Bahia; Benjamin O Patterson; Robert J Hinchliffe; Matthew M Thompson
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9.  Final 12-year follow-up of surgery versus surveillance in the UK Small Aneurysm Trial.

Authors:  J T Powell; L C Brown; J F Forbes; F G R Fowkes; R M Greenhalgh; C V Ruckley; S G Thompson
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10.  Mortality from ruptured abdominal aortic aneurysms: clinical lessons from a comparison of outcomes in England and the USA.

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2.  The state of complex endovascular abdominal aortic aneurysm repairs in the Vascular Quality Initiative.

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Review 7.  Epidemiology of Abdominal Aortic Aneurysm Repair in Brazil from 2008 to 2019 and Comprehensive Review of Nationwide Statistics Across the World.

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Review 8.  Abdominal Aortic Aneurysm: Evolving Controversies and Uncertainties.

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9.  Utilization of Advanced Cardiovascular Therapies in the United States and Canada: An Observational Study of New York and Ontario Administrative Data.

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Journal:  Circ Cardiovasc Qual Outcomes       Date:  2020-01-20

10.  Neutrophil Gelatinase-Associated Lipocalin as an Early Predictor of Contrast-Induced Nephropathy Following Endovascular Aortic Repair for Abdominal Aortic Aneurysm.

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