Efficient Synthetic Routes to (±)-Hippolachnin A, (±)-Gracilioethers E and F and the Alleged Structure of (±)-Gracilioether I.

Two monocyclic members in the gracilioether family were synthesized in only three steps. The monocyclic products were further elaborated into advanced precursors to hippolachnin A and gracilioether E, respectively. Gracilioether F and the alleged structure for gracilioether I were also synthesized using a late-stage C(sp3 )-H thermo-oxidation.