| Literature DB >> 27957710 |
Loo Keat Wei1, Anthony Au2, Lai Kuan Teh3, Huey Shi Lye4.
Abstract
Hypertension is a silent killer worldwide, caused by both genetic and environmental factors. Until now, genetic and genomic association studies of hypertension are reporting different degree of association on hypertension. Hence, it is essential to gather all the available information on the reported genetic loci and to determine if any biomarker(s) is/are significantly associated with hypertension. Current review concluded the potential biomarkers for hypertension, with regards to electrolyte and fluid transports, as well as sodium/potassium ions homeostasis, which are supported by the results of case-controls and meta-analyses.Entities:
Keywords: GWAS; Genetic; Hypertension; Meta-analysis; Polymorphism
Mesh:
Substances:
Year: 2017 PMID: 27957710 DOI: 10.1007/5584_2016_75
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622