Literature DB >> 27939975

Neuroprotection and secondary damage following spinal cord injury: concepts and methods.

Brett J Hilton1, Aaron J Moulson1, Wolfram Tetzlaff2.   

Abstract

Neuroprotection refers to the attenuation of pathophysiological processes triggered by acute injury to minimize secondary damage. The development of neuroprotective treatments represents a major goal in the field of spinal cord injury (SCI) research. In this review, we discuss the strengths and limitations of the methodologies employed to assess secondary damage and neuroprotection in preclinical models of traumatic SCI. We also discuss modelling issues and how new tools might be exploited to study secondary damage and neuroprotection.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  CNS injury; Neuroprotection; Secondary damage; Spinal cord injury

Mesh：

Substances：

Year:  2016        PMID： 27939975     DOI： 10.1016/j.neulet.2016.12.004

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  27 in total

1.  Cellular Inflammatory Response of the Spleen After Acute Spinal Cord Injury in Rat.

Authors:  Feng Wu; Xiao-Yan Ding; Xiao-Hui Li; Min-Jie Gong; Jia-Qi An; Jiang-Hua Lai; Sheng-Li Huang
Journal:  Inflammation       Date:  2019-10       Impact factor: 4.092

2.  IP3R-mediated intra-axonal Ca2+ release contributes to secondary axonal degeneration following contusive spinal cord injury.

Authors:  Ben C Orem; Arezoo Rajaee; David P Stirling
Journal:  Neurobiol Dis       Date:  2020-10-01       Impact factor: 5.996

3.  Repeat intravital imaging of the murine spinal cord reveals degenerative and reparative responses of spinal axons in real-time following a contusive SCI.

Authors:  Arezoo Rajaee; Mariah E Geisen; Alexandra K Sellers; David P Stirling
Journal:  Exp Neurol       Date:  2020-02-24       Impact factor: 5.330

4.  Effects of the Notch Signaling Pathway on Secondary Brain Changes Caused by Spinal Cord Injury in Mice.

Authors:  Chengcai Li; Shaoxin Huang; Wu Zhou; Zhiping Xie; Shenke Xie; Meihua Li
Journal:  Neurochem Res       Date:  2022-02-24       Impact factor: 3.996

5.  Hyperbaric Oxygen Therapy after Mid-Cervical Spinal Contusion Injury.

Authors:  Sara M F Turner; Michael D Sunshine; Vijayendran Chandran; Ashley J Smuder; David D Fuller
Journal:  J Neurotrauma       Date:  2022-05       Impact factor: 4.869

6.  [Icariin alleviates lipid peroxidation after spinal cord injury in rats].

Authors:  Xian-Sheng Ren; Wei Ding; Xiao-Yu Yang
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2018-06-20

7.  Neuroprotective effect of immunomodulatory peptides in rats with traumatic spinal cord injury.

Authors:  Dulce Parra-Villamar; Liliana Blancas-Espinoza; Elisa Garcia-Vences; Juan Herrera-García; Adrian Flores-Romero; Alberto Toscano-Zapien; Jonathan Vilchis Villa; Rodríguez Barrera-Roxana; Soria Zavala Karla; Antonio Ibarra; Raúl Silva-García
Journal:  Neural Regen Res       Date:  2021-07       Impact factor: 5.135

Review 8.  Ketogenic regimens for acute neurotraumatic events.

Authors:  Ceren Yarar-Fisher; Jia Li; Erika D Womack; Amal Alharbi; Oscar Seira; Kathleen L Kolehmainen; Ward T Plunet; Nima Alaeiilkhchi; Wolfram Tetzlaff
Journal:  Curr Opin Biotechnol       Date:  2021-01-11       Impact factor: 10.279

Review 9.  An Overview of Mesenchymal Stem Cell-based Therapy Mediated by Noncoding RNAs in the Treatment of Neurodegenerative Diseases.

Authors:  Yifei Luo; Wei Qiu; Buling Wu; Fuchun Fang
Journal:  Stem Cell Rev Rep       Date:  2021-08-04       Impact factor: 5.739

Review 10.  Stress-Activated Protein Kinases in Spinal Cord Injury: Focus on Roles of p38.

Authors:  Yoshitoshi Kasuya; Hiroki Umezawa; Masahiko Hatano
Journal:  Int J Mol Sci       Date:  2018-03-15       Impact factor: 5.923
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