Literature DB >> 27939763

Advanced age does not affect abdominal wall reconstruction outcomes using acellular dermal matrix: A comparative study using propensity score analysis.

Salvatore Giordano1, Mark Schaverien1, Patrick B Garvey1, Donald P Baumann1, Jun Liu1, Charles E Butler2.   

Abstract

BACKGROUND: We hypothesized that elderly patients (≥65 years) experience worse outcomes following abdominal wall reconstruction (AWR) for hernia or oncologic resection.
METHODS: We included all consecutive patients who underwent complex AWR using acellular dermal matrix (ADM) between 2005 and 2015. Propensity score analysis was performed for risk adjustment in multivariable analysis and for one-to-one matching. The primary outcome was hernia recurrence; the secondary outcomes included surgical site occurrence (SSO) and bulging.
RESULTS: Mean follow-up for the 511 patients was 31.4 months; 184 (36%) patients were elderly. The elderly and non-elderly groups had similar rates of hernia recurrence (7.6% vs 10.1%, respectively; p = 0.43) and SSO (24.5% vs 23.5%, respectively; p = 0.82). Bulging occurred significantly more often in elderly patients (6.5% vs 2.8%, respectively; p = 0.04). After adjustment through the propensity score, which included 130 pairs, these results persisted.
CONCLUSIONS: Contrary to our hypothesis, elderly patients did not have worse outcomes in AWR with ADM. Surgeons should not deny elderly patients AWR solely because of their age.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Abdominal wall; Acellular dermal matrix; Advanced age; Elderly; Hernia; Old; Postoperative complications; Strattice; SurgiMend; Surgical mesh

Mesh:

Year:  2016        PMID: 27939763     DOI: 10.1016/j.amjsurg.2016.10.023

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  3 in total

1.  Complex abdominal wall hernia repair with biologic mesh in elderly: a propensity matched analysis.

Authors:  S Gogna; R Latifi; A Policastro; K Prabhakaran; P Anderson; J Con; J Choi; D J Samson; J Butler
Journal:  Hernia       Date:  2020-01-24       Impact factor: 4.739

2.  Implications of Aging in Plastic Surgery.

Authors:  Danny S Roh; Adriana C Panayi; Shalender Bhasin; Dennis P Orgill; Indranil Sinha
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-01-14

Review 3.  Clinical applications of acellular dermal matrices: A review.

Authors:  Kyla Petrie; Cameron T Cox; Benjamin C Becker; Brendan J MacKay
Journal:  Scars Burn Heal       Date:  2022-01-19
  3 in total

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