Literature DB >> 2793836

Buspirone therapy for maladaptive behavior and anxiety in developmentally disabled persons.

J J Ratey1, R Sovner, E Mikkelsen, H E Chmielinski.   

Abstract

The authors used buspirone, a new anxiolytic agent that has a low side effect profile, to treat 14 developmentally disabled individuals who demonstrated anxiety as well as aggressive and self-injurious behaviors. Nine of the 14 individuals responded favorably to the drug. The authors present case reports for 3 of the responders and discuss the clinical implications of buspirone therapy.

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Year:  1989        PMID: 2793836

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  12 in total

Review 1.  Autism: current theories regarding its pathogenesis and implications for rational pharmacotherapy.

Authors:  J K Buitelaar; S H Willemsen-Swinkels
Journal:  Paediatr Drugs       Date:  2000 Jan-Feb       Impact factor: 3.022

Review 2.  5-HT1A partial agonists. What is their future?

Authors:  D A Glitz; R Pohl
Journal:  Drugs       Date:  1991-01       Impact factor: 9.546

3.  The effect of tryptophan depletion and enhancement on subjective and behavioural aggression in normal male subjects.

Authors:  A J Cleare; A J Bond
Journal:  Psychopharmacology (Berl)       Date:  1995-03       Impact factor: 4.530

4.  The use of buspirone with aggressive behavior.

Authors:  M Hillbrand; K Scott
Journal:  J Autism Dev Disord       Date:  1995-12

Review 5.  Multidisciplinary assessment and treatment of self-injurious behavior in autism spectrum disorder and intellectual disability: integration of psychological and biological theory and approach.

Authors:  Noha F Minshawi; Sarah Hurwitz; Danielle Morriss; Christopher J McDougle
Journal:  J Autism Dev Disord       Date:  2015-06

6.  Recurrent self-injurious behavior in forensic patients.

Authors:  M Hillbrand; J L Young; J H Krystal
Journal:  Psychiatr Q       Date:  1996

Review 7.  Self-injurious behaviour in autistic children: a neuro-developmental theory of social and environmental isolation.

Authors:  Darragh P Devine
Journal:  Psychopharmacology (Berl)       Date:  2013-09-21       Impact factor: 4.530

Review 8.  Medication treatment in subjects with autistic spectrum disorders.

Authors:  J K Buitelaar; S H Willemsen-Swinkels
Journal:  Eur Child Adolesc Psychiatry       Date:  2000       Impact factor: 4.785

Review 9.  Brain serotonin receptors and transporters: initiation vs. termination of escalated aggression.

Authors:  Aki Takahashi; Isabel M Quadros; Rosa M M de Almeida; Klaus A Miczek
Journal:  Psychopharmacology (Berl)       Date:  2010-09-03       Impact factor: 4.530

10.  Iontophoretic transdermal delivery of buspirone hydrochloride in hairless mouse skin.

Authors:  Mohammad Al-Khalili; Victor M Meidan; Bozena B Michniak
Journal:  AAPS PharmSci       Date:  2003
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