| Literature DB >> 2793590 |
T Shibata1, M Nishikawa, Y Tsurumi, S Takase, H Terano, M Kohsaka.
Abstract
FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. The mitogen-induced lymphocyte proliferation which had been suppressed by addition of immunosuppressive factor, was restored to a normal level by the addition of FR-901235. Furthermore, the subsequent administration of FR-901235 partially restored the impaired delayed-type hypersensitivity to sheep red blood cells in tumor-bearing mice.Entities:
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Year: 1989 PMID： 2793590 DOI： 10.7164/antibiotics.42.1356
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649