Literature DB >> 2793588

Isolation of isoflavonoids possessing antioxidant activity from the fermentation broth of Streptomyces sp.

K Komiyama1, S Funayama, Y Anraku, A Mita, Y Takahashi, S Omura, H Shimasaki.   

Abstract

Three antioxidant isoflavonoids characterized as 4',7,8-trihydroxyisoflavone (1), 3',4',7-trihydroxyisoflavone (2) and 8-chloro-3',4',5,7-tetrahydroxyisoflavone (3) were isolated from the cultured broth of Streptomyces sp. OH-1049. Among them, 3 is a novel isoflavonoid possessing a chlorine atom in the molecule. In in vitro studies, these antibiotics were found to possess antioxidant activity whereas showed almost no cytocidal activities against HeLa S3 cells.

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Year:  1989        PMID： 2793588     DOI： 10.7164/antibiotics.42.1344

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

1.  Formation of polyhydroxylated isoflavones from the soybean seed isoflavones daidzein and glycitein by bacteria isolated from tempe.

Authors:  K Klus; W Barz
Journal:  Arch Microbiol       Date:  1995-12       Impact factor: 2.552

2.  Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations.

Authors:  J Mark Weber; Andrew R Reeves; Ramya Seshadri; William H Cernota; Melissa C Gonzalez; Danielle L Gray; Roy K Wesley
Journal:  Appl Microbiol Biotechnol       Date:  2013-04-19       Impact factor: 4.813

3.  Biotransformation of Daidzein, Genistein, and Naringenin by Streptomyces Species Isolated from High-Altitude Soil of Nepal.

Authors:  Lasata Shrestha; Bishnu P Marasini; Suman Prakash Pradhan; Rajib Kumar Shrestha; Suraj Shrestha; Kamal Prasad Regmi; Bishnu Prasad Pandey
Journal:  Int J Microbiol       Date:  2021-06-19

Review 4.  Isolation, bioactivity, and production of ortho-hydroxydaidzein and ortho-hydroxygenistein.

Authors:  Te-Sheng Chang
Journal:  Int J Mol Sci       Date:  2014-04-03       Impact factor: 5.923

5.  Streptomyces-Derived Metabolites with Potential Photoprotective Properties-A Systematic Literature Review and Meta-Analysis on the Reported Chemodiversity.

Authors:  Jeysson Sánchez-Suárez; Ericsson Coy-Barrera; Luisa Villamil; Luis Díaz
Journal:  Molecules       Date:  2020-07-15       Impact factor: 4.411

Review 6.  Naturally Occurring Flavonoids and Isoflavonoids and Their Microbial Transformation: A Review.

Authors:  Jun-Fei Wang; Si-Si Liu; Zhi-Qiang Song; Tang-Chang Xu; Chuan-Sheng Liu; Ya-Ge Hou; Rong Huang; Shao-Hua Wu
Journal:  Molecules       Date:  2020-11-03       Impact factor: 4.411
  6 in total

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