Literature DB >> 2793586

Novel antitumor antibiotic phospholine. 1. Production, isolation and characterization.

T Ozasa1, K Suzuki, M Sasamata, K Tanaka, M Kobori, S Kadota, K Nagai, T Saito, S Watanabe, M Iwanami.   

Abstract

Phospholine was isolated as an antitumor antibiotic from the fermentation broth of Streptomyces hygroscopicus. Phospholine is an amphoteric compound which has an amino group and a phosphoric acid ester as functional groups. Phospholine shows strong activities against L1210, P388 and EL-4.

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Year:  1989        PMID： 2793586     DOI： 10.7164/antibiotics.42.1331

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  The plmS2-encoded cytochrome P450 monooxygenase mediates hydroxylation of phoslactomycin B in Streptomyces sp. strain HK803.

Authors:  Mohini S Ghatge; Kevin A Reynolds
Journal:  J Bacteriol       Date:  2005-12       Impact factor: 3.490

2.  Total synthesis of fostriecin: via a regio- and stereoselective polyene hydration, oxidation, and hydroboration sequence.

Authors:  Dong Gao; George A O'Doherty
Journal:  Org Lett       Date:  2010-09-03       Impact factor: 6.005

3.  Silyl glyoxylates. Conception and realization of flexible conjunctive reagents for multicomponent coupling.

Authors:  Gregory R Boyce; Stephen N Greszler; Jeffrey S Johnson; Xin Linghu; Justin T Malinowski; David A Nicewicz; Andrew D Satterfield; Daniel C Schmitt; Kimberly M Steward
Journal:  J Org Chem       Date:  2012-03-23       Impact factor: 4.354

Review 4.  Genetic manipulation of the biosynthetic process leading to phoslactomycins, potent protein phosphatase 2A inhibitors.

Authors:  Mohini Ghatge; Nadaraj Palaniappan; Suparna Das Choudhuri; Kevin Reynolds
Journal:  J Ind Microbiol Biotechnol       Date:  2006-04-12       Impact factor: 3.346

5.  Polarity inversion of donor-acceptor cyclopropanes: disubstituted δ-lactones via enantioselective iridium catalysis.

Authors:  Joseph Moran; Austin G Smith; Ryan M Carris; Jeffrey S Johnson; Michael J Krische
Journal:  J Am Chem Soc       Date:  2011-10-31       Impact factor: 15.419

6.  Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates.

Authors:  Stephen N Greszler; Justin T Malinowski; Jeffrey S Johnson
Journal:  Org Lett       Date:  2011-05-17       Impact factor: 6.005

7.  Genome sequence of Streptomyces auratus strain AGR0001, a phoslactomycin-producing actinomycete.

Authors:  Xiulin Han; Minggang Li; Zhanggui Ding; Jiangyuan Zhao; Kaiyan Ji; Mengliang Wen; Tao Lu
Journal:  J Bacteriol       Date:  2012-10       Impact factor: 3.490

8.  Application of a newly identified and characterized 18-o-acyltransferase in chemoenzymatic synthesis of selected natural and nonnatural bioactive derivatives of phoslactomycins.

Authors:  Mohini S Ghatge; Nadaraj Palaniappan; Ma'moun M Alhamadsheh; Jessica DiBari; Kevin A Reynolds
Journal:  Appl Environ Microbiol       Date:  2009-03-20       Impact factor: 4.792
  8 in total

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