Literature DB >> 27934602

Generation of human iPSCs from urine derived cells of a patient with a novel homozygous PAI-1 mutation.

Muhammad Zeeshan Afzal1, Melanie Gartz1, Ekaterina A Klyachko2, Sadiya Sana Khan2, Sanjiv J Shah2, Sweta Gupta3, Amy D Shapiro3, Douglas E Vaughan2, Jennifer L Strande4.   

Abstract

We have generated a human induced pluripotent stem cell (iPSC) line under feeder-free culture conditions using the urine derived cells (UCs) collected from subject with a novel homozygous Plasminogen Activator Inhibitor-1 (PAI-1 null) mutation. The Sendai virus (SeV) vector encoding pluripotent Yamanaka transcription factors was used at a low multiplicity of infection to reprogram the PAI-1 UCs.
Copyright © 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany. Published by Elsevier B.V. All rights reserved.

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Year:  2016        PMID： 27934602      PMCID： PMC5409870          DOI： 10.1016/j.scr.2016.11.010

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN： 1873-5061            Impact factor:   2.020


  13 in total

1.  Brief report: complete deficiency of plasminogen-activator inhibitor type 1 due to a frame-shift mutation.

Authors:  W P Fay; A D Shapiro; J L Shih; R R Schleef; D Ginsburg
Journal:  N Engl J Med       Date:  1992-12-10       Impact factor: 91.245

2.  Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence.

Authors:  David J Elzi; Yanlai Lai; Meihua Song; Kevin Hakala; Susan T Weintraub; Yuzuru Shiio
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-09       Impact factor: 11.205

3.  Human plasminogen activator inhibitor-1 (PAI-1) deficiency: characterization of a large kindred with a null mutation in the PAI-1 gene.

Authors:  W P Fay; A C Parker; L R Condrey; A D Shapiro
Journal:  Blood       Date:  1997-07-01       Impact factor: 22.113

Review 4.  Role of plasminogen activator inhibitor-1 in senescence and aging.

Authors:  Mesut Eren; Amanda E Boe; Ekaterina A Klyachko; Douglas E Vaughan
Journal:  Semin Thromb Hemost       Date:  2014-08-31       Impact factor: 4.180

5.  Generation of induced pluripotent stem cells from muscular dystrophy patients: efficient integration-free reprogramming of urine derived cells.

Authors:  Muhammad Z Afzal; Jennifer L Strande
Journal:  J Vis Exp       Date:  2015-01-28       Impact factor: 1.355

6.  PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.

Authors:  Mesut Eren; Amanda E Boe; Sheila B Murphy; Aaron T Place; Varun Nagpal; Luisa Morales-Nebreda; Daniela Urich; Susan E Quaggin; G R Scott Budinger; Gökhan M Mutlu; Toshio Miyata; Douglas E Vaughan
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-28       Impact factor: 11.205

7.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors:  Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

8.  The obstetric, gynaecological and fertility implications of homozygous PAI-1 deficiency: single-centre experience.

Authors:  M Heiman; S Gupta; A D Shapiro
Journal:  Haemophilia       Date:  2013-11-22       Impact factor: 4.287

9.  Myxoma viral serpin, Serp-1, a unique interceptor of coagulation and innate immune pathways.

Authors:  Kasinath Viswanathan; Liying Liu; Sepideh Vaziri; Erbin Dai; Jakob Richardson; Babajide Togonu-Bickersteth; Pracha Vatsya; Alexander Christov; Alexandra R Lucas
Journal:  Thromb Haemost       Date:  2006-03       Impact factor: 5.249

10.  SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence.

Authors:  Yan-Zhen Wan; Peng Gao; Shuang Zhou; Zhu-Qin Zhang; De-Long Hao; Li-Shan Lian; Yong-Jun Li; Hou-Zao Chen; De-Pei Liu
Journal:  Aging Cell       Date:  2014-07-18       Impact factor: 9.304
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  2 in total

1.  Generation of human iPSCs from urine derived cells of patient with a novel heterozygous PAI-1 mutation.

Authors:  Muhammad Zeeshan Afzal; Melanie Gartz; Ekaterina A Klyachko; Sadiya Sana Khan; Sanjiv J Shah; Sweta Gupta; Amy D Shapiro; Douglas E Vaughan; Jennifer L Strande
Journal:  Stem Cell Res       Date:  2016-12-09       Impact factor: 2.020

2.  Distinct effects of V617F and exon12-mutated JAK2 expressions on erythropoiesis in a human induced pluripotent stem cell (iPSC)-based model.

Authors:  Nungruthai Nilsri; Panchalee Jangprasert; Jaturawat Pawinwongchai; Nipan Israsena; Ponlapat Rojnuckarin
Journal:  Sci Rep       Date:  2021-03-04       Impact factor: 4.379
  2 in total

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