Literature DB >> 27934386

Ruthenium-Catalyzed Synthesis of β-Hydroxyamides from β-Ketonitriles in Water.

Rebeca González-Fernández1, Pascale Crochet1, Victorio Cadierno1.   

Abstract

An unprecedented hydration/transfer hydrogenation tandem process for the catalytic conversion of β-ketonitriles into synthetically useful β-hydroxyamides in water has been developed, making use of the ruthenium(II) complex [RuCl2(η6-p-cymene){P(4-C6H4F)2Cl}] in combination with sodium formate.

Entities:  

Year:  2016        PMID: 27934386     DOI: 10.1021/acs.orglett.6b03172

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis of functionalised β-keto amides by aminoacylation/domino fragmentation of β-enamino amides.

Authors:  Pavel Yanev; Plamen Angelov
Journal:  Beilstein J Org Chem       Date:  2018-10-10       Impact factor: 2.883

2.  Annulation cascade of arylnitriles with alkynes to stable delocalized PAH carbocations via intramolecular rhodium migration.

Authors:  Jiangliang Yin; Fulin Zhou; Lei Zhu; Mufan Yang; Yu Lan; Jingsong You
Journal:  Chem Sci       Date:  2018-05-29       Impact factor: 9.825

  2 in total

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