Literature DB >> 2793364

Is the high concentration of ascorbic acid in the eye an adaptation to intense solar irradiation?

T K Koskela1, G R Reiss, R F Brubaker, R D Ellefson.   

Abstract

Ascorbic acid is known to exist in high concentration in the aqueous humor of the eye in many species. It has been observed that diurnal mammals have a very high concentration in aqueous humor whereas nocturnal mammals do not. It has been hypothesized that ascorbic acid protects the eye from the harmful effects of sunlight. We have discovered that of two closely related species of spiny mice, the diurnal species (Acomys russatus) has a concentration in aqueous humor that is 35 times higher than that of the nocturnal species (Acomys cahirinus). Studies of these two species may be fruitful to extend what is known about adaptation of the eye to protect itself from intense solar radiation.

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Year:  1989        PMID： 2793364

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN： 0146-0404            Impact factor:   4.799


  6 in total

1.  Effects of ascorbic acid on UV light-mediated photoreceptor damage in isolated rat retina.

Authors:  Kazuhiro Tokuda; Charles F Zorumski; Yukitoshi Izumi
Journal:  Exp Eye Res       Date:  2007-01-12       Impact factor: 3.467

Review 2.  Chronobiology of interspecific interactions in a changing world.

Authors:  Noga Kronfeld-Schor; Marcel E Visser; Lucia Salis; Jan A van Gils
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2017-11-19       Impact factor: 6.237

Review 3.  The nocturnal bottleneck and the evolution of activity patterns in mammals.

Authors:  Menno P Gerkema; Wayne I L Davies; Russell G Foster; Michael Menaker; Roelof A Hut
Journal:  Proc Biol Sci       Date:  2013-07-03       Impact factor: 5.349

4.  The substructure of the suprachiasmatic nucleus: Similarities between nocturnal and diurnal spiny mice.

Authors:  Rotem Cohen; Noga Kronfeld-Schor; Chidambaram Ramanathan; Anna Baumgras; Laura Smale
Journal:  Brain Behav Evol       Date:  2010-02-05       Impact factor: 1.808

5.  Evidence of carrier mediated transport of ascorbic acid through mammalian cornea.

Authors:  Shivali Singla; D K Majumdar; Sachin Goyal; Gurudas Khilnani
Journal:  Saudi Pharm J       Date:  2011-03-31       Impact factor: 4.330

6.  Functional characterization and molecular identification of vitamin C transporter (SVCT2) in human corneal epithelial (HCEC) and retinal pigment epithelial (D407) cells.

Authors:  Varun Khurana; Aswani Dutt Vadlapudi; Ramya Krishna Vadlapatla; Dhananjay Pal; Ashim K Mitra
Journal:  Curr Eye Res       Date:  2014-07-11       Impact factor: 2.424
  6 in total

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