Literature DB >> 27933349

[Speech audiometric outcome parameters in clinical trials on hearing improvement].

J Müller1, S K Plontke1, T Rahne2.   

Abstract

BACKGROUND: When comparing clinical studies nationally and internationally, there is great heterogeneity in the applied audiometric outcome parameters. Beside different frequencies included in pure-tone audiometry and the resulting averages, the word recognition scores are measured at varying sound pressure levels, i.e., either with a fixed sound pressure level or with a fixed sensation level. However, a comparison of studies, e. g., in meta-analysis, requires comparable outcome parameters.
OBJECTIVE: In this study, the influence of speech-audiometric outcome parameters on the outcome reporting of hearing therapies is studied. PATIENTS AND METHODS: Before and after a conservative or a surgical treatment aimed at hearing improvement, 25 patients with hearing impairment were tested with the German Freiburg speech intelligibility test with monosyllables and numbers at various levels, and with the German Oldenburg sentence test in quiet. Additionally, 49 subjects with normal hearing were tested.
RESULTS: In a comparison of measurement methods (outcome parameters), the hearing improvement measured using constant sound pressure levels for speech audiometry was significantly greater and therefore more sensitive than using constant sensation levels.
CONCLUSION: To test changes in hearing in clinical studies, fixed sound pressure levels should be preferred to fixed sensation levels. For the development of standardized outcome parameters for measuring speech intelligibility in quiet, fixed sound pressure levels or measurement of speech reception thresholds should be selected.

Entities:  

Keywords:  Hearing loss; Rehabilitation; Speech audiometry; Speech discrimination tests; Speech reception threshold

Mesh:

Year:  2017        PMID: 27933349     DOI: 10.1007/s00106-016-0298-4

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  12 in total

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Authors:  Stefan K Plontke; Michael Bauer; Christoph Meisner
Journal:  Otol Neurotol       Date:  2007-09       Impact factor: 2.311

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Authors:  Lesli A Guthrie; Carol L Mackersie
Journal:  J Am Acad Audiol       Date:  2009-06       Impact factor: 1.664

9.  [Multicenter trial for sudden hearing loss therapy - planning and concept].

Authors:  S K Plontke; M Girndt; C Meisner; R Probst; I Oerlecke; M Richter; J Steighardt; G Dreier; A Weber; I Baumann; S Plößl; J Löhler; R Laszig; J A Werner; T Rahne
Journal:  HNO       Date:  2016-04       Impact factor: 1.284

10.  A software tool for pure‑tone audiometry. Classification of audiograms for inclusion of patients in clinical trials. English version.

Authors:  T Rahne; F Buthut; S Plößl; S K Plontke
Journal:  HNO       Date:  2016-03       Impact factor: 1.284

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  5 in total

1.  Minimal Reporting Standards for Active Middle Ear Hearing Implants.

Authors:  Hannes Maier; Uwe Baumann; Wolf-Dieter Baumgartner; Dirk Beutner; Marco D Caversaccio; Thomas Keintzel; Martin Kompis; Thomas Lenarz; Astrid Magele; Torsten Mewes; Alexander Müller; Tobias Rader; Torsten Rahne; Sebastian P Schraven; Burkard Schwab; Georg Mathias Sprinzl; Bernd Strauchmann; Ingo Todt; Thomas Wesarg; Barbara Wollenberg; Stefan K Plontke
Journal:  Audiol Neurootol       Date:  2018-09-07       Impact factor: 1.854

Review 2.  [Pitfalls in the statistical world].

Authors:  C Kiese-Himmel; S K Plontke
Journal:  HNO       Date:  2020-01       Impact factor: 1.284

3.  [Speech recognition with hearing aids for 10 standard audiograms].

Authors:  C Dörfler; T Hocke; A Hast; U Hoppe
Journal:  HNO       Date:  2020-01       Impact factor: 1.284

4.  Age-Related Decline of Speech Perception.

Authors:  Ulrich Hoppe; Thomas Hocke; Heinrich Iro
Journal:  Front Aging Neurosci       Date:  2022-06-22       Impact factor: 5.702

5.  Safety and audiological outcome in a case series of tertiary therapy of sudden hearing loss with a biodegradable drug delivery implant for controlled release of dexamethasone to the inner ear.

Authors:  Stefan K Plontke; Arne Liebau; Eric Lehner; Daniel Bethmann; Karsten Mäder; Torsten Rahne
Journal:  Front Neurosci       Date:  2022-09-20       Impact factor: 5.152

  5 in total

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