| Literature DB >> 27931949 |
Dominik Schuster1, Jasmin Rickmeyer1, Mike Gajdiss1, Thorsten Thye2, Stephan Lorenzen2, Marion Reif1, Michaele Josten1, Christiane Szekat1, Luís D R Melo1, Ricarda M Schmithausen1, Florian Liégeois3, Hans-Georg Sahl1, Jean-Paul J Gonzalez4, Michael Nagel4, Gabriele Bierbaum5.
Abstract
The species Staphylococcus argenteus was separated recently from Staphylococcus aureus (Tong S.Y., F. Schaumburg, M.J. Ellington, J. Corander, B. Pichon, F. Leendertz, S.D. Bentley, J. Parkhill, D.C. Holt, G. Peters, and P.M. Giffard, 2015). The objective of this work was to characterise the genome of a non-human S. argenteus strain, which had been isolated from the faeces of a wild-living western lowland gorilla in Gabon, and analyse the spectrum of this species in matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The full genome sequence revealed a scarcity of virulence genes and absence of resistance genes, indicating a decreased virulence potential compared to S. aureus and the human methicillin-resistant S. argenteus isolate MSHR1132T. Spectra obtained by MALDI-TOF MS and the analysis of available sequences in the genome databases identified several MALDI-TOF MS signals that clearly differentiate S. argenteus, the closely related Staphylococcus schweitzeri and S. aureus. In conclusion, in the absence of biochemical tests that identify the three species, mass spectrometry should be employed as method of choice.Entities:
Keywords: Gorilla gorilla ssp. gorilla; MALDI-TOF MS; Staphylococcus argenteus; Staphylococcus aureus; Staphylococcus schweitzeri; Virulence determinants
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Year: 2016 PMID： 27931949 DOI： 10.1016/j.ijmm.2016.11.003
Source DB: PubMed Journal: Int J Med Microbiol ISSN： 1438-4221 Impact factor: 3.473