Literature DB >> 27930860

Long-Term Real-Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer.

Sing Shy Liow1, Qingqing Dou1, Dan Kai1, Zibiao Li1, Sigit Sugiarto1, Chris Yee Yung Yu2, Ryan Tsz Kin Kwok2, Xiaohong Chen3, Yun-Long Wu3, Seow Theng Ong4, Atish Kizhakeyil4, Navin K Verma4, Ben Zhong Tang2, Xian Jun Loh1,5,6.   

Abstract

A new drug concentration meter is developed. In vivo drug release can be monitored precisely via a self-indicating drug delivery system consisting of a new aggregation-induced emission thermoresponsive hydrogel. By taking the advantage of a self-indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  AIE micelles; drug delivery; fluorescence dyes; imaging; thermogels

Mesh：

Substances：

Year:  2016        PMID： 27930860     DOI： 10.1002/smll.201603404

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  11 in total

1.  Photoacoustic Imaging Quantifies Drug Release from Nanocarriers via Redox Chemistry of Dye-Labeled Cargo.

Authors:  Ananthakrishnan Soundaram Jeevarathinam; Jeanne E Lemaster; Fang Chen; Eric Zhao; Jesse V Jokerst
Journal:  Angew Chem Int Ed Engl       Date:  2020-01-24       Impact factor: 15.336

Review 2.  Recent Developments in Nanosensors for Imaging Applications in Biological Systems.

Authors:  Guoxin Rong; Erin E Tuttle; Ashlyn Neal Reilly; Heather A Clark
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2019-03-11       Impact factor: 10.745

Review 3.  AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications.

Authors:  Hui Gao; Xin Zhao; Sijie Chen
Journal:  Molecules       Date:  2018-02-14       Impact factor: 4.411

4.  Sustained Release of Melatonin from GelMA Liposomes Reduced Osteoblast Apoptosis and Improved Implant Osseointegration in Osteoporosis.

Authors:  Long Xiao; Jiayi Lin; Ruoyu Chen; Yu Huang; Yu Liu; Jiaxiang Bai; Gaoran Ge; Xiaopeng Shi; Yong Chen; Jiandong Shi; Lu Aiqing; Huilin Yang; Dechun Geng; Zhirong Wang
Journal:  Oxid Med Cell Longev       Date:  2020-05-28       Impact factor: 6.543

5.  Mitochondria-Responsive Drug Release along with Heat Shock Mediated by Multifunctional Glycolipid Micelles for Precise Cancer Chemo-Phototherapy.

Authors:  Yanan Tan; Yun Zhu; Lijuan Wen; Xiqin Yang; Xuan Liu; Tingting Meng; Suhuan Dai; Yuan Ping; Hong Yuan; Fuqiang Hu
Journal:  Theranostics       Date:  2019-01-24       Impact factor: 11.556

Review 6.  Recent Advances in Aggregation-Induced Emission Active Materials for Sensing of Biologically Important Molecules and Drug Delivery System.

Authors:  Geeta A Zalmi; Ratan W Jadhav; Harshad A Mirgane; Sheshanath V Bhosale
Journal:  Molecules       Date:  2021-12-27       Impact factor: 4.411

7.  Supramolecular thermogels from branched PCL-containing polyurethanes.

Authors:  Qianyu Lin; Jason Y C Lim; Kun Xue; Celestine P T Chee; Xian Jun Loh
Journal:  RSC Adv       Date:  2020-10-26       Impact factor: 4.036

8.  Novel Treatment for Glioblastoma Delivered by a Radiation Responsive and Radiopaque Hydrogel.

Authors:  Mathilde Bouché; Yuxi C Dong; Saad Sheikh; Kimberly Taing; Deeksha Saxena; Jessica C Hsu; Minna H Chen; Ryan D Salinas; Hongjun Song; Jason A Burdick; Jay Dorsey; David P Cormode
Journal:  ACS Biomater Sci Eng       Date:  2021-06-23

Review 9.  Self-Assemblable Polymer Smart-Blocks for Temperature-Induced Injectable Hydrogel in Biomedical Applications.

Authors:  Thai Thanh Hoang Thi; Le Hoang Sinh; Dai Phu Huynh; Dai Hai Nguyen; Cong Huynh
Journal:  Front Chem       Date:  2020-01-31       Impact factor: 5.221

Review 10.  Fluorescent Polymers Conspectus.

Authors:  Guillermo Ahumada; Magdalena Borkowska
Journal:  Polymers (Basel)       Date:  2022-03-11       Impact factor: 4.329
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