Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy.

Literature DB >> 27928170

Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy.

Claudia Pérez-Martínez¹, Marta Regueiro-Purriños¹, Beatriz Fernández-Martínez¹, José R Altónaga¹, José M Gonzalo-Orden¹, María J García-Iglesias¹.

Abstract

A vertebral mass in a dog with an acute onset paraparesis was identified by magnetic resonance imaging. A poorly differentiated hemangiosarcoma was diagnosed by histopathology and immunohistochemistry. Endothelial nitric oxide synthase could be a new differential marker for poorly differentiated hemangiosarcoma in dogs. Immunohistochemical detection of p53 phosphorylated at Serine392, p53, CD117, and CD44 suggest targets for design of therapeutic strategies.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2016 PMID： 27928170 PMCID： PMC5109625

Source DB: PubMed Journal: Can Vet J ISSN： 0008-5286 Impact factor: 1.008

17 in total

1. Ser392 phosphorylation regulates the oncogenic function of mutant p53.

Authors: Damian B S Yap; Jung-Kuang Hsieh; Shan Zhong; Vicky Heath; Barry Gusterson; Tim Crook; Xin Lu
Journal: Cancer Res Date: 2004-07-15 Impact factor: 12.701

2. The significance of p53 and retinoblastoma pathways in canine hemangiosarcoma.

Authors: Kayoko Yonemaru; Hiroki Sakai; Mami Murakami; Atsushi Kodama; Takashi Mori; Tokuma Yanai; Kohji Maruo; Toshiaki Masegi
Journal: J Vet Med Sci Date: 2007-03 Impact factor: 1.267

3. Endothelial nitric oxide synthase as a marker for human endothelial progenitor cells.

Authors: Wei Qiao; Lingying Niu; Zhao Liu; Tong Qiao; Changjian Liu
Journal: Tohoku J Exp Med Date: 2010-05 Impact factor: 1.848

4. CD31 expression in intratumoral macrophages: a potential diagnostic pitfall.

Authors: J K McKenney; S W Weiss; A L Folpe
Journal: Am J Surg Pathol Date: 2001-09 Impact factor: 6.394

5. Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment.

Authors: Erika L Spaeth; Adam M Labaff; Bryan P Toole; Ann Klopp; Michael Andreeff; Frank C Marini
Journal: Cancer Res Date: 2013-07-09 Impact factor: 12.701

Review 10. The myofibroblast: phenotypic characterization as a prerequisite to understanding its functions in translational medicine.

Authors: B Eyden
Journal: J Cell Mol Med Date: 2007-12-22 Impact factor: 5.310

1 in total

1. Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats.

Authors: Mylène Auger; Silke Hecht; Cary M Springer
Journal: Front Vet Sci Date: 2021-01-07

1 in total

Magnetic resonance imaging and immunohistochemistry of primary vertebral hemangiosarcoma in a dog and implications for diagnosis and therapy.

1. Ser392 phosphorylation regulates the oncogenic function of mutant p53.

2. The significance of p53 and retinoblastoma pathways in canine hemangiosarcoma.

3. Endothelial nitric oxide synthase as a marker for human endothelial progenitor cells.

4. CD31 expression in intratumoral macrophages: a potential diagnostic pitfall.

5. Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment.

6. Tumorigenic conversion of endothelial cells.

7. Immunohistochemical detection of CD31 antigen in normal and neoplastic canine endothelial cells.

8. An immunohistochemical analysis of canine haemangioma and haemangiosarcoma.

9. Immunohistochemical evaluation of vascular urinary bladder tumors from cows with enzootic hematuria.

Review 10. The myofibroblast: phenotypic characterization as a prerequisite to understanding its functions in translational medicine.

1. Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats.