Literature DB >> 27927900

Questions and Assays.

Nancy Kleckner1.   

Abstract

The Thomas Hunt Morgan Medal is awarded to an individual Genetics Society of America member for lifetime achievement in the field of genetics. It recognizes the full body of work of an exceptional geneticist. The 2016 recipient is Nancy Kleckner, who has made many significant contributions to our understanding of chromosomes and the mechanisms of inheritance. Kleckner has made seminal achievements in several different research areas, including bacterial transposition, chromosome organization, and meiosis. She has repeatedly combined traditional genetic approaches with molecular biology, microscopy, physics, and modeling-unprecedented applications of these methods at the time, but which have now become commonplace. Indeed, she is widely recognized as one of the leaders in bringing meiosis research into the modern era. Notably, her laboratory played a key role in elucidating the mechanism that initiates meiotic recombination, has helped to decipher the "strand gymnastics" of recombination, and is beginning to provide insight into the enigmatic phenomenon of crossover interference.
Copyright © 2016 by the Genetics Society of America.

Mesh:

Year:  2016        PMID: 27927900      PMCID: PMC5161267          DOI: 10.1534/genetics.116.197608

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  38 in total

1.  The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination.

Authors:  N Hunter; N Kleckner
Journal:  Cell       Date:  2001-07-13       Impact factor: 41.582

2.  Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formation.

Authors:  Yuval Blat; Reine U Protacio; Neil Hunter; Nancy Kleckner
Journal:  Cell       Date:  2002-12-13       Impact factor: 41.582

3.  Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.

Authors:  S Keeney; C N Giroux; N Kleckner
Journal:  Cell       Date:  1997-02-07       Impact factor: 41.582

4.  Topoisomerase II mediates meiotic crossover interference.

Authors:  Liangran Zhang; Shunxin Wang; Shen Yin; Soogil Hong; Keun P Kim; Nancy Kleckner
Journal:  Nature       Date:  2014-07-13       Impact factor: 49.962

5.  Preferential cis action of IS10 transposase depends upon its mode of synthesis.

Authors:  C Jain; N Kleckner
Journal:  Mol Microbiol       Date:  1993-07       Impact factor: 3.501

6.  The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site.

Authors:  S Bolland; N Kleckner
Journal:  Cell       Date:  1996-01-26       Impact factor: 41.582

7.  Translational control of IS10 transposition.

Authors:  R W Simons; N Kleckner
Journal:  Cell       Date:  1983-09       Impact factor: 41.582

8.  Recombination proteins mediate meiotic spatial chromosome organization and pairing.

Authors:  Aurora Storlazzi; Silvana Gargano; Gwenael Ruprich-Robert; Matthieu Falque; Michelle David; Nancy Kleckner; Denise Zickler
Journal:  Cell       Date:  2010-04-02       Impact factor: 41.582

9.  ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

Authors:  Rita S Cha; Nancy Kleckner
Journal:  Science       Date:  2002-07-26       Impact factor: 47.728

Review 10.  The role of chromosomal retention of noncoding RNA in meiosis.

Authors:  Da-Qiao Ding; Tokuko Haraguchi; Yasushi Hiraoka
Journal:  Chromosome Res       Date:  2013-12       Impact factor: 5.239

View more
  1 in total

Review 1.  Crossover Interference: Shedding Light on the Evolution of Recombination.

Authors:  Sarah P Otto; Bret A Payseur
Journal:  Annu Rev Genet       Date:  2019-08-20       Impact factor: 16.830

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.