Hiroko Matsumoto1, Nicholas D Colacchio2, Frank J Schwab3, Virginie Lafage3, Evan D Sheha2, David P Roye2, Michael G Vitale2. 1. Department of Orthopaedic Surgery, Columbia University Medical Center, 3959 Broadway Avenue, 8 North, New York, NY, USA. Electronic address: hm2174@columbia.edu. 2. Department of Orthopaedic Surgery, Columbia University Medical Center, 3959 Broadway Avenue, 8 North, New York, NY, USA. 3. Department of Orthopaedic Surgery, New York University Medical School, New York, NY, USA.
Abstract
STUDY DESIGN: Retrospective review of prospective multicenter adolescent idiopathic scoliosis (AIS) database. OBJECTIVES: To investigate the effect of decreased lumbar lordosis (LL) on measured pelvic tilt (PT) after posterior spinal instrumentation and fusion for AIS and to test the hypothesis that lumbar spinal fusion resulting in mismatched LL is associated with increased PT. SUMMARY OF BACKGROUND DATA: Interaction between the spine and pelvis highly influences global sagittal alignment (GSA). In adults, correlation between health-related quality of life measures and LL proportional to a patient-specific pelvic incidence (PI) has been established, although the implications of poor sagittal alignment are less well-defined in AIS. This observation warrants further examination of regional spine contour and its relation to the pelvis in AIS. METHODS: The authors queried a prospective multicenter database for AIS patients who underwent posterior spinal instrumentation and fusion with lowest instrumented vertebra between L2 and L5 and identified 155 patients with minimum 2 years' follow-up. Lumbar lordosis (T12-S1), LL within fusion, LL below fusion, GSA, PT, and PI were measured preoperatively and at 2 years. Change in PT was compared between patients with matched or mismatched LL based on a common clinical definition (LL = PI + 10) and a research-driven model (LL = 0.56 PI + 33.43). RESULTS: Thirty-eight percent of patients had decreased LL from before surgery to 2 years after surgery. These patients had significantly higher rates of increased PT (73%) than patients without decreased LL (40%). Multivariate regression demonstrated that change in LL, LL within fusion, and GSA had a significant predictive effect on PT (p < .001). Using either definition of LL, patients with LL less than 2 standard deviations from predicted values were more likely to have increased PT. CONCLUSIONS: Iatrogenic loss of LL commonly occurs in spine fusion for AIS and is associated with a reciprocal increase in PT. As such, spinal fusion in AIS can have unintended effects on sagittal alignment with currently uninvestigated potential consequences in the future.
STUDY DESIGN: Retrospective review of prospective multicenter adolescent idiopathic scoliosis (AIS) database. OBJECTIVES: To investigate the effect of decreased lumbar lordosis (LL) on measured pelvic tilt (PT) after posterior spinal instrumentation and fusion for AIS and to test the hypothesis that lumbar spinal fusion resulting in mismatched LL is associated with increased PT. SUMMARY OF BACKGROUND DATA: Interaction between the spine and pelvis highly influences global sagittal alignment (GSA). In adults, correlation between health-related quality of life measures and LL proportional to a patient-specific pelvic incidence (PI) has been established, although the implications of poor sagittal alignment are less well-defined in AIS. This observation warrants further examination of regional spine contour and its relation to the pelvis in AIS. METHODS: The authors queried a prospective multicenter database for AIS patients who underwent posterior spinal instrumentation and fusion with lowest instrumented vertebra between L2 and L5 and identified 155 patients with minimum 2 years' follow-up. Lumbar lordosis (T12-S1), LL within fusion, LL below fusion, GSA, PT, and PI were measured preoperatively and at 2 years. Change in PT was compared between patients with matched or mismatched LL based on a common clinical definition (LL = PI + 10) and a research-driven model (LL = 0.56 PI + 33.43). RESULTS: Thirty-eight percent of patients had decreased LL from before surgery to 2 years after surgery. These patients had significantly higher rates of increased PT (73%) than patients without decreased LL (40%). Multivariate regression demonstrated that change in LL, LL within fusion, and GSA had a significant predictive effect on PT (p < .001). Using either definition of LL, patients with LL less than 2 standard deviations from predicted values were more likely to have increased PT. CONCLUSIONS: Iatrogenic loss of LL commonly occurs in spine fusion for AIS and is associated with a reciprocal increase in PT. As such, spinal fusion in AIS can have unintended effects on sagittal alignment with currently uninvestigated potential consequences in the future.
Authors: Bryan Ang; Renaud Lafage; Jonathan Charles Elysée; Tejbir S Pannu; Mathieu Bannwarth; Brandon B Carlson; Frank J Schwab; Han Jo Kim; Virginie Lafage Journal: Global Spine J Date: 2020-04-01