Monika Szulińska1, Damian Skrypnik2, Marzena Ratajczak3, Joanna Karolkiewicz3, Edyta Madry4, Katarzyna Musialik1, Jaroslaw Walkowiak5, Hieronim Jakubowski6, Pawel Bogdański1. 1. Department of Education and Obesity Treatment and Metabolic Disorders, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland. 2. Department of Internal Medicine, Metabolic Disorders and Hypertension, Poznań University of Medical Sciences, ul. Szamarzewskiego 82, 60-569 Poznań, Poland. 3. Department of Physiology, Biochemistry and Hygiene, Poznań University School of Physical Education, ul. Królowej Jadwigi 27/39, 61-871 Poznań, Poland. 4. Department of Physiology, Poznań University of Medical Sciences, ul. Swiecickiego 6, 60-781 Poznań, Poland. 5. Department of Pediatric Gastroenterology and Metabolic Diseases, Poznań University of Medical Sciences, ul. Szpitalna 27/33, 60-572 Poznań, Poland. 6. Department of Microbiology, Biochemistry and Molecular Genetics, Rutgers University, New Jersey Medical School, International Center for Public Health, 225 Warren Street, Room E230P Newark, New Jersey 07103-3535, USA; Department of Biochemistry and Biotechnology, Poznań University of Life Sciences, Dojazd Str. 11, 60-632 Poznan, Poland; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego Str. 12/14, 61-704 Poznan, Poland.
Abstract
OBJECTIVE: Obesity is associated with kidney defects. Physical activity is a key element in the treatment of obesity. The aim of this study was to compare the effect of endurance and endurance-strength training on kidney function in abdominally obese women. METHODS:Forty-fourabdominally obese women were randomized to endurance training or endurance-strength training, three times a week for 3 months. Before and after the intervention, kidney function was assessed by measuring blood creatinine, urine creatinine, and urine albumin levels, and the albumin-to-creatinine ratio and glomerular filtration rate (GFR) were calculated. RESULTS:Renal hyperperfusion was present in both groups before the study. Following both types of physical activity, similar modifications of the investigated parameters were observed, but with no significant between-group differences. Both courses of training led to a significant increase in blood creatinine and a subsequent decrease in the GFR. A significant increase in urine creatinine and album levels, though not exceeding the range for microalbuminuria, was not accompanied by any difference in the albumin-to-creatinine ratio after endurance-strength training alone. CONCLUSION: Three months of either endurance or endurance-strength training has a favorable and comparable effect on renal function in abdominally obese women with renal hyperfiltration.
RCT Entities:
OBJECTIVE:Obesity is associated with kidney defects. Physical activity is a key element in the treatment of obesity. The aim of this study was to compare the effect of endurance and endurance-strength training on kidney function in abdominally obesewomen. METHODS: Forty-four abdominally obesewomen were randomized to endurance training or endurance-strength training, three times a week for 3 months. Before and after the intervention, kidney function was assessed by measuring blood creatinine, urine creatinine, and urine albumin levels, and the albumin-to-creatinine ratio and glomerular filtration rate (GFR) were calculated. RESULTS:Renal hyperperfusion was present in both groups before the study. Following both types of physical activity, similar modifications of the investigated parameters were observed, but with no significant between-group differences. Both courses of training led to a significant increase in blood creatinine and a subsequent decrease in the GFR. A significant increase in urine creatinine and album levels, though not exceeding the range for microalbuminuria, was not accompanied by any difference in the albumin-to-creatinine ratio after endurance-strength training alone. CONCLUSION: Three months of either endurance or endurance-strength training has a favorable and comparable effect on renal function in abdominally obesewomen with renal hyperfiltration.
Authors: Michael J LaMonte; JoAnn E Manson; Andrea K Chomistek; Joseph C Larson; Cora E Lewis; Jennifer W Bea; Karen C Johnson; Wenjun Li; Liviu Klein; Andrea Z LaCroix; Marcia L Stefanick; Jean Wactawski-Wende; Charles B Eaton Journal: JACC Heart Fail Date: 2018-09-05 Impact factor: 12.035
Authors: Qian Wang; Lingzhong Xu; Jiajia Li; Long Sun; Wenzhe Qin; Gan Ding; Jing Zhu; Jiao Zhang; Zihang Yu; Su Xie Journal: Int J Environ Res Public Health Date: 2018-04-19 Impact factor: 3.390
Authors: Gian Pietro Emerenziani; Dafne Ferrari; Maria Grazia Vaccaro; Maria Chiara Gallotta; Silvia Migliaccio; Andrea Lenzi; Carlo Baldari; Laura Guidetti Journal: PLoS One Date: 2018-05-11 Impact factor: 3.240
Authors: Jacek Wilczyński; Marta Mierzwa-Molenda; Natalia Habik-Tatarowska Journal: Int J Environ Res Public Health Date: 2020-06-11 Impact factor: 3.390