Literature DB >> 27926728

Pharmacology: Inside-out receptor inhibition.

Thomas P Sakmar1, Thomas Huber1.   

Abstract

Mesh：

Year:  2016        PMID： 27926728     DOI： 10.1038/nature20486

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  12 in total

1.  Intracellular allosteric antagonism of the CCR9 receptor.

Authors:  Christine Oswald; Mathieu Rappas; James Kean; Andrew S Doré; James C Errey; Kirstie Bennett; Francesca Deflorian; John A Christopher; Ali Jazayeri; Jonathan S Mason; Miles Congreve; Robert M Cooke; Fiona H Marshall
Journal:  Nature       Date:  2016-12-07       Impact factor: 49.962

2.  A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

Authors:  A De Lean; J M Stadel; R J Lefkowitz
Journal:  J Biol Chem       Date:  1980-08-10       Impact factor: 5.157

3.  Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.

Authors:  Ling Qin; Irina Kufareva; Lauren G Holden; Chong Wang; Yi Zheng; Chunxia Zhao; Gustavo Fenalti; Huixian Wu; Gye Won Han; Vadim Cherezov; Ruben Abagyan; Raymond C Stevens; Tracy M Handel
Journal:  Science       Date:  2015-01-22       Impact factor: 47.728

4.  Multiple binding sites for small-molecule antagonists at the CC chemokine receptor 2.

Authors:  Annelien J M Zweemer; Indira Nederpelt; Hilde Vrieling; Sarah Hafith; Maarten L J Doornbos; Henk de Vries; Jeffrey Abt; Raymond Gross; Dean Stamos; John Saunders; Martine J Smit; Adriaan P Ijzerman; Laura H Heitman
Journal:  Mol Pharmacol       Date:  2013-07-22       Impact factor: 4.436

5.  Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12.

Authors:  Christopher T Veldkamp; Christoph Seibert; Francis C Peterson; Norberto B De la Cruz; John C Haugner; Harihar Basnet; Thomas P Sakmar; Brian F Volkman
Journal:  Sci Signal       Date:  2008-09-16       Impact factor: 8.192

6.  Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex.

Authors:  Qiuxiang Tan; Ya Zhu; Jian Li; Zhuxi Chen; Gye Won Han; Irina Kufareva; Tingting Li; Limin Ma; Gustavo Fenalti; Jing Li; Wenru Zhang; Xin Xie; Huaiyu Yang; Hualiang Jiang; Vadim Cherezov; Hong Liu; Raymond C Stevens; Qiang Zhao; Beili Wu
Journal:  Science       Date:  2013-09-12       Impact factor: 47.728

7.  Crystal structure of the β2 adrenergic receptor-Gs protein complex.

Authors:  Søren G F Rasmussen; Brian T DeVree; Yaozhong Zou; Andrew C Kruse; Ka Young Chung; Tong Sun Kobilka; Foon Sun Thian; Pil Seok Chae; Els Pardon; Diane Calinski; Jesper M Mathiesen; Syed T A Shah; Joseph A Lyons; Martin Caffrey; Samuel H Gellman; Jan Steyaert; Georgios Skiniotis; William I Weis; Roger K Sunahara; Brian K Kobilka
Journal:  Nature       Date:  2011-07-19       Impact factor: 49.962

8.  Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Authors:  Yanyong Kang; X Edward Zhou; Xiang Gao; Yuanzheng He; Wei Liu; Andrii Ishchenko; Anton Barty; Thomas A White; Oleksandr Yefanov; Gye Won Han; Qingping Xu; Parker W de Waal; Jiyuan Ke; M H Eileen Tan; Chenghai Zhang; Arne Moeller; Graham M West; Bruce D Pascal; Ned Van Eps; Lydia N Caro; Sergey A Vishnivetskiy; Regina J Lee; Kelly M Suino-Powell; Xin Gu; Kuntal Pal; Jinming Ma; Xiaoyong Zhi; Sébastien Boutet; Garth J Williams; Marc Messerschmidt; Cornelius Gati; Nadia A Zatsepin; Dingjie Wang; Daniel James; Shibom Basu; Shatabdi Roy-Chowdhury; Chelsie E Conrad; Jesse Coe; Haiguang Liu; Stella Lisova; Christopher Kupitz; Ingo Grotjohann; Raimund Fromme; Yi Jiang; Minjia Tan; Huaiyu Yang; Jun Li; Meitian Wang; Zhong Zheng; Dianfan Li; Nicole Howe; Yingming Zhao; Jörg Standfuss; Kay Diederichs; Yuhui Dong; Clinton S Potter; Bridget Carragher; Martin Caffrey; Hualiang Jiang; Henry N Chapman; John C H Spence; Petra Fromme; Uwe Weierstall; Oliver P Ernst; Vsevolod Katritch; Vsevolod V Gurevich; Patrick R Griffin; Wayne L Hubbell; Raymond C Stevens; Vadim Cherezov; Karsten Melcher; H Eric Xu
Journal:  Nature       Date:  2015-07-22       Impact factor: 49.962

9.  Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.

Authors:  Dean P Staus; Ryan T Strachan; Aashish Manglik; Biswaranjan Pani; Alem W Kahsai; Tae Hun Kim; Laura M Wingler; Seungkirl Ahn; Arnab Chatterjee; Ali Masoudi; Andrew C Kruse; Els Pardon; Jan Steyaert; William I Weis; R Scott Prosser; Brian K Kobilka; Tommaso Costa; Robert J Lefkowitz
Journal:  Nature       Date:  2016-07-13       Impact factor: 49.962

10.  Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.

Authors:  Yi Zheng; Ling Qin; Natalia V Ortiz Zacarías; Henk de Vries; Gye Won Han; Martin Gustavsson; Marta Dabros; Chunxia Zhao; Robert J Cherney; Percy Carter; Dean Stamos; Ruben Abagyan; Vadim Cherezov; Raymond C Stevens; Adriaan P IJzerman; Laura H Heitman; Andrew Tebben; Irina Kufareva; Tracy M Handel
Journal:  Nature       Date:  2016-12-07       Impact factor: 49.962
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  1 in total

Review 1.  Trends in GPCR drug discovery: new agents, targets and indications.

Authors:  Alexander S Hauser; Misty M Attwood; Mathias Rask-Andersen; Helgi B Schiöth; David E Gloriam
Journal:  Nat Rev Drug Discov       Date:  2017-10-27       Impact factor: 84.694
  1 in total

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