Mária Jakó1, Andrea Surányi1, Márta Janáky2, Péter Klivényi3, László Kaizer4, László Vécsei3, György Bártfai1, Gábor Németh1. 1. a Department of Obstetrics and Gynecology , University of Szeged , Szeged , Hungary. 2. b Department of Ophthalmology , University of Szeged , Szeged , Hungary. 3. c Department of Neurology , University of Szeged , Szeged , Hungary. 4. d Department of Pathology , University of Szeged , Szeged , Hungary.
Abstract
PURPOSE: Plasmapheresis in pregnancy adversely affects maternal hemodynamics, however there are studies suggesting it to reduce pregnancy loss in immunological diseases when medication is more harmful to the fetus. The overall optimal plasmapheresis treatment protocol remains unknown. MATERIALS AND METHODS: A pregnant with neuromyelitis optica was followed up after receiving six volumes of fresh frozen plasma via plasmapheresis. RESULTS: The placenta compensated the hemodynamic change until the 33rd week of gestation, resulting a small for gestational age, otherwise healthy girl. CONCLUSIONS: More research is needed on plasma exchange during pregnancy because in our observation placental circulation can adapt to the change in blood pressure.
PURPOSE: Plasmapheresis in pregnancy adversely affects maternal hemodynamics, however there are studies suggesting it to reduce pregnancy loss in immunological diseases when medication is more harmful to the fetus. The overall optimal plasmapheresis treatment protocol remains unknown. MATERIALS AND METHODS: A pregnant with neuromyelitis optica was followed up after receiving six volumes of fresh frozen plasma via plasmapheresis. RESULTS: The placenta compensated the hemodynamic change until the 33rd week of gestation, resulting a small for gestational age, otherwise healthy girl. CONCLUSIONS: More research is needed on plasma exchange during pregnancy because in our observation placental circulation can adapt to the change in blood pressure.