Literature DB >> 27921198

[Metabolic surgery or conservative measures as therapy of obese type 2 diabetics?]

Udo Jahn1, Thomas Schubert2, Sibylle Schlepp3, Heinz Jürgen Deuber4.   

Abstract

After bariatric surgery there are some favourable effects on comorbidities of obesity as glucose and lipid metabolism besides weight loss. Therefore surgical measures targeting at improvement of such metabolic disorders especially diabetes type 2 has been called "metabolic surgery". The complexity of its underlying metabolic mechanisms is not yet clear, but restriction of energy and weight loss (maintenance) seem to be the cornerstones.Risks of these procedures which are drawn of the established methods of bariatric surgery are reported to be relatively low in qualified centers. Being an elective operation special focus has to be set on mortality and morbidity, numbers of therapeutic failure and redo-surgery. Multiple irreversible and not seldom severe, potentially life-threatening consequences of bariatric surgery require consequent interdisciplinary postsurgery care and therapy throughout the whole life, especially substitution therapy of deficiencies due to post-operative malassimilation, if necessary. Little is known about long term consequences of modified anatomy and function of digestive system caused by surgery, and there may be a delay of (many) years until manifestation of clinical problems.Obese diabetics (BMI ≥ 35 kg/m2) should primarily be treated conservatively in an "individualized" way. Metabolic surgery should not be considered earlier than failure of the conservative approach has to be stated (in this case as an "ultima ratio" in well defined trials). A broader use of metabolic surgery beyond this narrow frame is not yet supported by long-term evidence-based data showing its value and safety.

Entities:  

Keywords:  Bariatric surgery; Energy restriction; Long term consequences; Metabolic surgery; Side effects; Type-2-diabetes

Mesh:

Year:  2016        PMID: 27921198     DOI: 10.1007/s10354-016-0532-4

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  86 in total

1.  [Individualized prevention of type 2 diabetes].

Authors:  N Stefan; A Fritsche; H-U Häring
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2009-07       Impact factor: 1.513

2.  Effects of weight loss, weight cycling, and weight loss maintenance on diabetes incidence and change in cardiometabolic traits in the Diabetes Prevention Program.

Authors:  Linda M Delahanty; Qing Pan; Kathleen A Jablonski; Vanita R Aroda; Karol E Watson; George A Bray; Steven E Kahn; Jose C Florez; Leigh Perreault; Paul W Franks
Journal:  Diabetes Care       Date:  2014-07-14       Impact factor: 19.112

Review 3.  Risk of completed suicide after bariatric surgery: a systematic review.

Authors:  C Peterhänsel; D Petroff; G Klinitzke; A Kersting; B Wagner
Journal:  Obes Rev       Date:  2013-01-09       Impact factor: 9.213

4.  Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes.

Authors:  Philip R Schauer; Deepak L Bhatt; John P Kirwan; Kathy Wolski; Stacy A Brethauer; Sankar D Navaneethan; Ali Aminian; Claire E Pothier; Esther S H Kim; Steven E Nissen; Sangeeta R Kashyap
Journal:  N Engl J Med       Date:  2014-03-31       Impact factor: 91.245

Review 5.  [Nutrient Deficiencies after Bariatric Surgery - Systematic Literature Review and Suggestions for Diagnostics and Treatment].

Authors:  C Stroh; F Benedix; F Meyer; T Manger
Journal:  Zentralbl Chir       Date:  2013-07-03       Impact factor: 0.942

6.  Predictors of long-term mortality after bariatric surgery performed in Veterans Affairs medical centers.

Authors:  David Arterburn; Edward H Livingston; Tracy Schifftner; Leila C Kahwati; William G Henderson; Matthew L Maciejewski
Journal:  Arch Surg       Date:  2009-10

Review 7.  Metabolic surgery for type 2 diabetes with BMI <35 kg/m(2) : an endocrinologist's perspective.

Authors:  Harold E Lebovitz
Journal:  Obes Surg       Date:  2013-06       Impact factor: 4.129

8.  Weight-loss maintenance in successful weight losers: surgical vs non-surgical methods.

Authors:  D S Bond; S Phelan; T M Leahey; J O Hill; R R Wing
Journal:  Int J Obes (Lond)       Date:  2008-12-02       Impact factor: 5.095

Review 9.  Mechanisms of Weight Regain following Weight Loss.

Authors:  Erik Scott Blomain; Dara Anne Dirhan; Michael Anthony Valentino; Gilbert Won Kim; Scott Arthur Waldman
Journal:  ISRN Obes       Date:  2013-04-16

Review 10.  Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials.

Authors:  Viktoria L Gloy; Matthias Briel; Deepak L Bhatt; Sangeeta R Kashyap; Philip R Schauer; Geltrude Mingrone; Heiner C Bucher; Alain J Nordmann
Journal:  BMJ       Date:  2013-10-22
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.